AC   CVCL_9U66
DR   cancercelllines; CVCL_9U66
DR   Wikidata; Q54972051
RX   PubMed=7494248;
RX   PubMed=10022544;
CC   Group: Retrovirus packaging cell line.
CC   Problematic cell line: Contaminated. Grand-parent cell line (TE 671) has been shown to be a RD derivative.
CC   Population: Caucasian.
CC   Sequence variation: Mutation; HGNC; 7989; NRAS; Simple; p.Gln61His (c.183A>T); ClinVar=VCV000373003; Zygosity=Heterozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 11998; TP53; Simple; p.Arg248Trp (c.742C>T); ClinVar=VCV000012347; Zygosity=Homozygous (from parent cell line).
CC   Transfected with: UniProtKB; P03355; Moloney murine leukemia virus (MoMLV) gag-pol.
CC   Transfected with: UniProtKB; P00722; Escherichia coli lacZ.
CC   Derived from site: In situ; Pelvis, muscle; UBERON=UBERON_0001325.
DI   NCIt; C8971; Embryonal rhabdomyosarcoma
DI   ORDO; Orphanet_99757; Embryonal rhabdomyosarcoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_9U65 ! TELac2
SX   Female
AG   7Y
CA   Cancer cell line
DT   Created: 23-02-16; Last updated: 05-10-23; Version: 13
RX   PubMed=7494248; DOI=10.1128/JVI.69.12.7430-7436.1995;
RA   Cosset F.-L., Takeuchi Y., Battini J.-L., Weiss R.A., Collins M.K.L.;
RT   "High-titer packaging cells producing recombinant retroviruses
RT   resistant to human serum.";
RL   J. Virol. 69:7430-7436(1995).
RX   PubMed=10022544; DOI=10.1089/10430349950018986;
RA   Duisit G., Salvetti A., Moullier P., Cosset F.-L.;
RT   "Functional characterization of adenoviral/retroviral chimeric vectors
RT   and their use for efficient screening of retroviral producer cell
RT   lines.";
RL   Hum. Gene Ther. 10:189-200(1999).