ID   MNNG/HOS/DXR1000
AC   CVCL_9U38
DR   cancercelllines; CVCL_9U38
DR   Wikidata; Q54906272
RX   PubMed=10854558;
CC   Population: Caucasian.
CC   Selected for resistance to: ChEBI; CHEBI:28748; Doxorubicin (Adriablastin; Adriamycin).
CC   Sequence variation: Gene deletion; HGNC; 1787; CDKN2A; Zygosity=Homozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 11998; TP53; Simple; p.Arg156Pro (c.467G>C); ClinVar=VCV000634768; Zygosity=Homozygous (from parent cell line).
CC   Derived from site: In situ; Bone, right femur; UBERON=UBERON_0000981.
DI   NCIt; C9145; Osteosarcoma
DI   ORDO; Orphanet_668; Osteosarcoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_0439 ! MNNG/HOS Cl #5
SX   Female
AG   13Y
CA   Cancer cell line
DT   Created: 23-02-16; Last updated: 05-10-23; Version: 12
//
RX   PubMed=10854558; DOI=10.3892/or.7.4.859;
RA   Oda Y., Matsumoto Y., Harimaya K., Iwamoto Y., Tsuneyoshi M.;
RT   "Establishment of new multidrug-resistant human osteosarcoma cell
RT   lines.";
RL   Oncol. Rep. 7:859-866(2000).
//