ID   MDA-MB-231-5a-D-TbetaFluc/Rluc-ZsGreen
AC   CVCL_9U33
SY   5a-D-Luc-ZsGreen
DR   cancercelllines; CVCL_9U33
DR   Wikidata; Q54904595
RX   PubMed=26691676;
CC   Group: Triple negative breast cancer (TNBC) cell line.
CC   Population: Caucasian.
CC   Sequence variation: Gene deletion; HGNC; 1787; CDKN2A; Zygosity=Homozygous (from parent cell line).
CC   Sequence variation: Gene deletion; HGNC; 1788; CDKN2B; Zygosity=Homozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 1097; BRAF; Simple; p.Gly464Val (c.1391G>T); ClinVar=VCV000040364; Zygosity=Heterozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 6407; KRAS; Simple; p.Gly13Asp (c.38G>A); ClinVar=VCV000012580; Zygosity=Heterozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 11730; TERT; Simple; c.1-124C>T (c.228C>T) (C228T); Zygosity=Unspecified; Note=In promoter (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 11998; TP53; Simple; p.Arg280Lys (c.839G>A); ClinVar=VCV000376657; Zygosity=Homozygous (from parent cell line).
CC   Transfected with: UniProtKB; P08659; Firefly luciferase.
CC   Transfected with: UniProtKB; P27652; Renilla-type luciferase.
CC   Transfected with: UniProtKB; Q9U6Y4; Zoanthus sp. chromoprotein FP538 (modified and distributed as ZsGreen1).
CC   Derived from site: Metastatic; Pleural effusion; UBERON=UBERON_0000175.
DI   NCIt; C5214; Breast adenocarcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_9U32 ! MDA-MB-231-5a-D-TbetaFluc/Rluc
SX   Female
AG   51Y
CA   Cancer cell line
DT   Created: 23-02-16; Last updated: 05-10-23; Version: 17
//
RX   PubMed=26691676; DOI=10.3892/ijo.2015.3300;
RA   Sudo H., Tsuji A.B., Sugyo A., Takuwa H., Masamoto K., Tomita Y.,
RA   Suzuki N., Imamura T., Koizumi M., Saga T.;
RT   "Establishment and evaluation of a new highly metastatic tumor cell
RT   line 5a-D-Luc-ZsGreen expressing both luciferase and green fluorescent
RT   protein.";
RL   Int. J. Oncol. 48:525-532(2016).
//