ID   COLO 239F
AC   CVCL_9975
SY   COLO 239; COLO #239; Colo 239F; COLO239F; Colo239F; COLOF; COLO-F; Colorado 239F
DR   cancercelllines; CVCL_9975
DR   Cosmic; 888990
DR   Cosmic; 928709
DR   GEO; GSM162934
DR   Wikidata; Q54814079
RX   PubMed=1697409;
RX   PubMed=6277475;
RX   PubMed=7379029;
RX   PubMed=9354451;
RX   PubMed=15048078;
RX   PubMed=17516929;
CC   Sequence variation: Gene deletion; HGNC; 1787; CDKN2A; Zygosity=Homozygous (PubMed=9354451).
CC   Sequence variation: Mutation; HGNC; 1097; BRAF; Simple; p.Val600Glu (c.1799T>A); ClinVar=VCV000013961; Zygosity=Unspecified (PubMed=15048078).
CC   Omics: Transcriptome analysis by microarray.
DI   NCIt; C3224; Melanoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Male
AG   25Y
CA   Cancer cell line
DT   Created: 06-06-12; Last updated: 05-10-23; Version: 15
//
RX   PubMed=1697409;
RA   Chenevix-Trench G., Martin N.G., Ellem K.A.O.;
RT   "Gene expression in melanoma cell lines and cultured melanocytes:
RT   correlation between levels of c-src-1, c-myc and p53.";
RL   Oncogene 5:1187-1193(1990).
//
RX   PubMed=6277475;
RA   Frampton R.J., Suva L.J., Eisman J.A., Findlay D.M., Moore G.E.,
RA   Moseley J.M., Martin T.J.;
RT   "Presence of 1,25-dihydroxyvitamin D3 receptors in established human
RT   cancer cell lines in culture.";
RL   Cancer Res. 42:1116-1119(1982).
//
RX   PubMed=7379029; DOI=10.1002/1097-0142(19800501)45:9<2311::AID-CNCR2820450914>3.0.CO;2-W;
RA   Moore G.E., Woods L.K., Quinn L.A., Morgan R.T., Semple T.U.;
RT   "Characterization of cell lines from four undifferentiated human
RT   malignancies.";
RL   Cancer 45:2311-2323(1980).
//
RX   PubMed=9354451;
RA   Castellano M., Pollock P.M., Walters M.K., Sparrow L.E., Down L.M.,
RA   Gabrielli B.G., Parsons P.G., Hayward N.K.;
RT   "CDKN2A/p16 is inactivated in most melanoma cell lines.";
RL   Cancer Res. 57:4868-4875(1997).
//
RX   PubMed=15048078; DOI=10.1038/sj.onc.1207563;
RA   Pavey S., Johansson P., Packer L., Taylor J., Stark M.S., Pollock P.M.,
RA   Walker G.J., Boyle G.M., Harper U., Cozzi S.-J., Hansen K., Yudt L.,
RA   Schmidt C., Hersey P., Ellem K.A.O., O'Rourke M.G.E., Parsons P.G.,
RA   Meltzer P.S., Ringner M., Hayward N.K.;
RT   "Microarray expression profiling in melanoma reveals a BRAF mutation
RT   signature.";
RL   Oncogene 23:4060-4067(2004).
//
RX   PubMed=17516929; DOI=10.1111/j.1600-0749.2007.00375.x;
RA   Johansson P., Pavey S., Hayward N.K.;
RT   "Confirmation of a BRAF mutation-associated gene expression signature
RT   in melanoma.";
RL   Pigment Cell Res. 20:216-221(2007).
//