ID   UKF-NB-4
AC   CVCL_9907
SY   UKF-NB4
DR   cancercelllines; CVCL_9907
DR   Wikidata; Q54990365
RX   PubMed=8543403;
RX   PubMed=16151587;
RX   PubMed=19147553;
RX   PubMed=24466371;
CC   Doubling time: 19.5-20.3 hours (PubMed=8543403).
CC   Sequence variation: Mutation; HGNC; 11998; TP53; Simple; p.Cys176Phe (c.527G>T); ClinVar=VCV000376569; Zygosity=Unspecified (PubMed=19147553).
CC   Derived from site: Metastatic; Bone marrow; UBERON=UBERON_0002371.
DI   NCIt; C3270; Neuroblastoma
DI   ORDO; Orphanet_635; Neuroblastoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
CA   Cancer cell line
DT   Created: 06-06-12; Last updated: 05-10-23; Version: 16
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RX   PubMed=8543403; DOI=10.1002/(SICI)1097-0215(19960103)65:1<90::AID-IJC16>3.0.CO;2-M;
RA   Cinatl J. Jr., Vogel J.-U., Cinatl J., Weber B., Rabenau H.F., Novak M.,
RA   Kornhuber B., Doerr H.-W.;
RT   "Long-term productive human cytomegalovirus infection of a human
RT   neuroblastoma cell line.";
RL   Int. J. Cancer 65:90-96(1996).
//
RX   PubMed=16151587;
RA   Bedrnicek J., Vicha A., Jarosova M., Holzerova M., Cinatl J. Jr.,
RA   Michaelis M., Cinatl J., Eckschlager T.;
RT   "Characterization of drug-resistant neuroblastoma cell lines by
RT   comparative genomic hybridization.";
RL   Neoplasma 52:415-419(2005).
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RX   PubMed=19147553; DOI=10.1158/0008-5472.CAN-08-1856;
RA   Michaelis M., Rothweiler F., Klassert D., von Deimling A., Weber K.,
RA   Fehse B., Kammerer B., Doerr H.-W., Cinatl J. Jr.;
RT   "Reversal of P-glycoprotein-mediated multidrug resistance by the
RT   murine double minute 2 antagonist nutlin-3.";
RL   Cancer Res. 69:416-421(2009).
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RX   PubMed=24466371; DOI=10.1593/tlo.13544;
RA   Loschmann N., Michaelis M., Rothweiler F., Zehner R., Cinatl J.,
RA   Voges Y., Sharifi M., Riecken K., Meyer J., von Deimling A.,
RA   Fichtner I., Ghafourian T., Westermann F., Cinatl J. Jr.;
RT   "Testing of SNS-032 in a panel of human neuroblastoma cell lines with
RT   acquired resistance to a broad range of drugs.";
RL   Transl. Oncol. 6:685-696(2013).
//