ID WA09 AC CVCL_9773 SY WA 09; WA-09; WA9; H9; H9.hESCs; H9 ESC; H9 hES; H9ES; GE09; WAe003-A; WICELLe003-A; WAe009-A; WA09-PCBC; PCBC02hse2014030502; SC14-067; UKERe008-A DR BTO; BTO_0006062 DR CLO; CLO_0037313 DR 4DN; 4DNSR9WBB58Z DR BioGRID_ORCS_Cell_line; 1321 DR BioSample; SAMN03471903 DR BioSamples; SAMEA7769668 DR CCRID; 3101HUMSCSP302 DR CCRID; 3101HUMSCSP307 DR ENCODE; ENCBS013BRF DR ENCODE; ENCBS061KRP DR ENCODE; ENCBS113LZP DR ENCODE; ENCBS140HIH DR ENCODE; ENCBS156LDX DR ENCODE; ENCBS220TZB DR ENCODE; ENCBS277KDR DR ENCODE; ENCBS298AAA DR ENCODE; ENCBS299AAA DR ENCODE; ENCBS300AAA DR ENCODE; ENCBS315DEY DR ENCODE; ENCBS375GFI DR ENCODE; ENCBS377MXB DR ENCODE; ENCBS399JWQ DR ENCODE; ENCBS410BMR DR ENCODE; ENCBS417MAQ DR ENCODE; ENCBS477SFO DR ENCODE; ENCBS485PGF DR ENCODE; ENCBS532LWE DR ENCODE; ENCBS616QKE DR ENCODE; ENCBS656LSW DR ENCODE; ENCBS692FVF DR ENCODE; ENCBS703ZDS DR ENCODE; ENCBS741LLD DR ENCODE; ENCBS757OPX DR ENCODE; ENCBS769EPD DR ENCODE; ENCBS808UWK DR ENCODE; ENCBS853WXF DR ENCODE; ENCBS883RFB DR ENCODE; ENCBS996IWU DR GEO; GSM239975 DR GEO; GSM288333 DR GEO; GSM288335 DR GEO; GSM288397 DR GEO; GSM347923 DR GEO; GSM383878 DR GEO; GSM383879 DR GEO; GSM384100 DR GEO; GSM500936 DR GEO; GSM569191 DR GEO; GSM569192 DR GEO; GSM579901 DR GEO; GSM579902 DR GEO; GSM603054 DR GEO; GSM603055 DR GEO; GSM605307 DR GEO; GSM605310 DR GEO; GSM605314 DR GEO; GSM605316 DR GEO; GSM605324 DR GEO; GSM616127 DR GEO; GSM616128 DR GEO; GSM616129 DR GEO; GSM627785 DR GEO; GSM637777 DR GEO; GSM665037 DR GEO; GSM667608 DR GEO; GSM667609 DR GEO; GSM667610 DR GEO; GSM667611 DR GEO; GSM667612 DR GEO; GSM667613 DR GEO; GSM667616 DR GEO; GSM667619 DR GEO; GSM667620 DR GEO; GSM667621 DR GEO; GSM667622 DR GEO; GSM667623 DR GEO; GSM667625 DR GEO; GSM667626 DR GEO; GSM667628 DR GEO; GSM667629 DR GEO; GSM667630 DR GEO; GSM667631 DR GEO; GSM667632 DR GEO; GSM667633 DR GEO; GSM667634 DR GEO; GSM667635 DR GEO; GSM667636 DR GEO; GSM667637 DR GEO; GSM667638 DR GEO; GSM667639 DR GEO; GSM667640 DR GEO; GSM667643 DR GEO; GSM669899 DR GEO; GSM669901 DR GEO; GSM670053 DR GEO; GSM674603 DR GEO; GSM706044 DR GEO; GSM706059 DR GEO; GSM706060 DR GEO; GSM706061 DR GEO; GSM706062 DR GEO; GSM706063 DR GEO; GSM706064 DR GEO; GSM706066 DR GEO; GSM706071 DR GEO; GSM706076 DR GEO; GSM755488 DR GEO; GSM755491 DR GEO; GSM816629 DR GEO; GSM856731 DR GEO; GSM860961 DR GEO; GSM860962 DR GEO; GSM860963 DR GEO; GSM862733 DR GEO; GSM927236 DR GEO; GSM997555 DR GEO; GSM997556 DR GEO; GSM997557 DR GEO; GSM1040243 DR GEO; GSM1040313 DR GEO; GSM1084832 DR GEO; GSM1084835 DR GEO; GSM1084943 DR GEO; GSM1084944 DR GEO; GSM1084992 DR GEO; GSM1085015 DR GEO; GSM1215278 DR GEO; GSM1215279 DR GEO; GSM1227088 DR GEO; GSM1489249 DR GEO; GSM1489460 DR GEO; GSM1589800 DR GEO; GSM1589812 DR GEO; GSM1589932 DR GEO; GSM1589944 DR GEO; GSM1658377 DR hPSCreg; WAe009-A DR IGRhCellID; H9%20p25-2 DR IGRhCellID; H9%20p34 DR LINCS_LDP; ES-1001 DR NIHhESC; NIHhESC-10-0062 DR PRIDE; PXD003903 DR PRIDE; PXD006271 DR SKIP; SKIP001452 DR SKIP; SKIP001935 DR TOKU-E; 4223 DR WiCell; wa09 DR WiCell; wa09-cgmp-material DR WiCell; wa09-matched-research DR WiCell; wa09-pcbc DR Wikidata; Q27555433 RX PubMed=9804556; RX PubMed=14745950; RX PubMed=16388305; RX PubMed=16919167; RX PubMed=17570852; RX PubMed=17572666; RX PubMed=20641038; RX PubMed=20736931; RX PubMed=21295703; RX PubMed=21936705; RX PubMed=21983960; RX PubMed=22514597; RX PubMed=22802639; RX PubMed=23117585; RX PubMed=24259714; RX PubMed=27293150; RX PubMed=27476965; RX PubMed=27688775; RX PubMed=28435121; RX PubMed=28445466; RX PubMed=28664172; RX PubMed=29246576; RX PubMed=29861859; RX PubMed=30388422; RX PubMed=35805069; WW Info; -; -; https://news.wisc.edu/nih-reapproves-wicells-h9-and-three-other-wisconsin-stem-cell-lines-for-federally-funded-research/ WW Info; ENCODE; -; http://genome.ucsc.edu/ENCODE/protocols/cell/human/BG02ES_and_H9ES_Myers_protocols.pdf WW Info; StemCellDB; -; https://stemcelldb.nih.gov/cellLineDetails/Agilent/13 WW Info; StRAP; -; https://strap.nci.nih.gov/celline_detail.php?sample_id=88 CC Group: Clinical grade pluripotent cell line. CC Part of: ENCODE project common cell types; tier 3. CC Part of: NHBLI Progenitor Cell Biology Consortium (PCBC) collection. CC From: University of Wisconsin; Madison; USA. CC Registration: NIH Human Embryonic Stem Cell Registry; NIHhESC-10-0062. CC Registration: Swiss research registry; BAG-hES-IMP-0016. CC Registration: UK Stem Cell Bank (UKSCB); Steering comm. appl. SCSC06-18/SCSC11-06. CC HLA typing: A*02:03; B*35,44; C*04,07; DQB1*05,06; DRB1*15,16:01; DRB5*01 (PubMed=16919167). CC Sequence variation: Mutation; HGNC; HGNC:11998; TP53; Simple; p.Pro151Ser (c.451C>T); ClinVar=VCV000012370; Zygosity=Unspecified; Note=Somatic mutation acquired during proliferation (PubMed=28445466). CC Sequence variation: Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg181His (c.542G>A); ClinVar=VCV000142320; Zygosity=Unspecified; Note=Somatic mutation acquired during proliferation (PubMed=28445466). CC Sequence variation: Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg248Gln (c.743G>A); ClinVar=VCV000012356; Zygosity=Unspecified; Note=Somatic mutation acquired during proliferation (PubMed=28445466). CC Sequence variation: Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg267Trp (c.799C>T); ClinVar=VCV000141764; Zygosity=Unspecified; Note=Somatic mutation acquired during proliferation (PubMed=28445466). CC Omics: Genomics; ChIP-seq; H2AK5ac. CC Omics: Genomics; ChIP-seq; H2BK12ac. CC Omics: Genomics; ChIP-seq; H2BK15ac. CC Omics: Genomics; ChIP-seq; H2BK5ac. CC Omics: Genomics; ChIP-seq; H3K18ac. CC Omics: Genomics; ChIP-seq; H3K23ac. CC Omics: Genomics; ChIP-seq; H3K23me2. CC Omics: Genomics; ChIP-seq; H3K27ac. CC Omics: Genomics; ChIP-seq; H3K27me3. CC Omics: Genomics; ChIP-seq; H3K36me3. CC Omics: Genomics; ChIP-seq; H3K4ac. CC Omics: Genomics; ChIP-seq; H3K4me1. CC Omics: Genomics; ChIP-seq; H3K4me2. CC Omics: Genomics; ChIP-seq; H3K4me3. CC Omics: Genomics; ChIP-seq; H3K56ac. CC Omics: Genomics; ChIP-seq; H3K79me1. CC Omics: Genomics; ChIP-seq; H3K79me2. CC Omics: Genomics; ChIP-seq; H3K9ac. CC Omics: Genomics; ChIP-seq; H3K9me3. CC Omics: Genomics; ChIP-seq; H4K20me1. CC Omics: Genomics; ChIP-seq; H4K5ac. CC Omics: Genomics; ChIP-seq; H4K8ac. CC Omics: Genomics; ChIP-seq; H4K91ac. CC Omics: Genomics; DNA methylation analysis. CC Omics: Genomics; Whole exome sequencing. CC Omics: Genomics; Whole genome sequencing. CC Omics: Proteomics. CC Omics: Proteomics; PTM; Phosphorylation. CC Omics: Proteomics; Subcellular; Mitochondrion. CC Omics: Transcriptomics; Microarray. CC Omics: Transcriptomics; RNAseq. CC Omics: Transcriptomics; Serial analysis of gene expression (SAGE). CC Omics: Variations; Array-based CGH. CC Omics: Variations; SNP array analysis. CC Anecdotal: WA01, WA07, WA09, WA13 and WA14 were the first human embryonic stem cells to be established. CC Derived from site: In situ; Blastocyst; UBERON=UBERON_0000358. CC Cell type: Embryonic stem cell; CL=CL_0002322. ST Source(s): PubMed=16919167; PubMed=29246576; WiCell=wa09 ST Amelogenin: X ST CSF1PO: 11 ST D13S317: 9 ST D16S539: 12,13 ST D18S51: 13 ST D19S433: 12,15 ST D21S11: 30 ST D2S1338: 18,24 ST D3S1358: 13,16 ST D5S818: 11,12 ST D7S820: 9,11 ST D8S1179: 8,14 ST FGA: 26,28 ST Penta D: 9,13 ST Penta E: 11,14 ST TH01: 9.3 ST TPOX: 10,11 ST vWA: 17 OX NCBI_TaxID=9606; ! Homo sapiens (Human) SX Female AG Blastocyst stage CA Embryonic stem cell DT Created: 06-06-12; Last updated: 10-04-25; Version: 41 // RX PubMed=9804556; DOI=10.1126/science.282.5391.1145; RA Thomson J.A., Itskovitz-Eldor J., Shapiro S.S., Waknitz M.A., RA Swiergiel J.J., Marshall V.S., Jones J.M.; RT "Embryonic stem cell lines derived from human blastocysts."; RL Science 282:1145-1147(1998). // RX PubMed=14745950; DOI=10.1002/dvdy.10431; RA Carpenter M.K., Rosler E.S., Fisk G.J., Brandenberger R., Ares X., RA Miura T., Lucero M.T., Rao M.S.; RT "Properties of four human embryonic stem cell lines maintained in a RT feeder-free culture system."; RL Dev. Dyn. 229:243-258(2004). // RX PubMed=16388305; DOI=10.1038/nbt1177; RA Ludwig T.E., Levenstein M.E., Jones J.M., Berggren W.T., Mitchen E.R., RA Frane J.L., Crandall L.J., Daigh C.A., Conard K.R., Piekarczyk M.S., RA Llanas R.A., Thomson J.A.; RT "Derivation of human embryonic stem cells in defined conditions."; RL Nat. 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Biotechnol. 25:803-816(2007). // RX PubMed=20641038; DOI=10.1002/stem.471; PMCID=PMC2996086; RA Gutierrez-Aranda I., Ramos-Mejia V., Bueno C., Munoz-Lopez M., RA Real P.J., Macia A., Sanchez L., Ligero G., Garcia-Parez J.L., RA Menendez P.; RT "Human induced pluripotent stem cells develop teratoma more RT efficiently and faster than human embryonic stem cells regardless the RT site of injection."; RL Stem Cells 28:1568-1570(2010). // RX PubMed=20736931; DOI=10.1038/mt.2010.179; PMCID=PMC2997587; RA Ramos-Mejia V., Melen Frajlich G.J., Sanchez L., Gutierrez-Aranda I., RA Ligero G., Cortes J.L., Real P.J., Bueno C., Menendez P.; RT "Nodal/activin signaling predicts human pluripotent stem cell lines RT prone to differentiate toward the hematopoietic lineage."; RL Mol. 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