ID   CLB-Ge1
AC   CVCL_9530
SY   CLB-Ge
DR   ArrayExpress; E-MTAB-6654
DR   cancercelllines; CVCL_9530
DR   PRIDE; PXD011187
DR   Wikidata; Q54813560
RX   DOI=10.1007/0-306-46872-7_2;
RX   PubMed=7705946;
RX   PubMed=18923523;
RX   PubMed=20160348;
RX   PubMed=30459281;
CC   Sequence variation: Mutation; HGNC; HGNC:427; ALK; Simple; p.Phe1174Val (c.3520T>G); ClinVar=VCV000065670; Zygosity=Unspecified (PubMed=18923523; PubMed=30459281).
CC   Omics: Proteomics; PTM; Phosphorylation.
CC   Omics: Transcriptomics; RNAseq.
CC   Derived from site: Metastatic; Bone marrow; UBERON=UBERON_0002371.
DI   NCIt; C3270; Neuroblastoma
DI   ORDO; Orphanet_635; Neuroblastoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
OI   CVCL_9531 ! CLB-Ge2
SX   Male
AG   1Y6M
CA   Cancer cell line
DT   Created: 06-06-12; Last updated: 10-04-25; Version: 15
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RX   DOI=10.1007/0-306-46872-7_2;
RA   Thiele, Carol Jeanne
RT   "Neuroblastoma.";
RL   (In book chapter) Human cell culture. Vol. 1. Cancer cell lines part 1; Masters, John R.W. & Palsson, Bernhard Orn (eds.); pp.21-53; Kluwer Academic Publishers; New York; USA (1999).
//
RX   PubMed=30459281; DOI=10.1126/scisignal.aar5680;
RA   Van den Eynden, Jimmy
RA   Umapathy, Ganesh
RA   Ashouri, Arghavan
RA   Cervantes-Madrid, Diana
RA   Szydzik, Joanna
RA   Ruuth, Kristina
RA   Koster, Jan
RA   Larsson, Erik
RA   Guan, Ji-Kui
RA   Palmer, Ruth Helen
RA   Hallberg, Bengt
RT   "Phosphoproteome and gene expression profiling of ALK inhibition in
RT   neuroblastoma cell lines reveals conserved oncogenic pathways.";
RL   Sci. Signal. 11:eaar5680.1-eaar5680.16(2018).
//
RX   PubMed=7705946; DOI=10.1002/ijc.2910610208;
RA   Combaret, Valerie
RA   Turc-Carel, Claude
RA   Thiesse, Philippe
RA   Rebillard, Anne-Catherine
RA   Frappaz, Didier
RA   Haus, Odile
RA   Philip, Thierry
RA   Favrot, Marie-Christine
RT   "Sensitive detection of numerical and structural aberrations of
RT   chromosome 1 in neuroblastoma by interphase fluorescence in situ
RT   hybridization. Comparison with restriction fragment length
RT   polymorphism and conventional cytogenetic analyses.";
RL   Int. J. Cancer 61:185-191(1995).
//
RX   PubMed=20160348; DOI=10.1172/JCI41013; PMCID=PMC2827960;
RA   Bouzas-Rodriguez, Jimena
RA   Cabrera, Jorge Ruben
RA   Delloye-Bourgeois, Celine
RA   Ichim, Gabriel
RA   Delcros, Jean-Guy
RA   Raquin, Marie-Anne
RA   Rousseau, Raphael
RA   Combaret, Valerie
RA   Benard, Jean
RA   Tauszig-Delamasure, Servane
RA   Mehlen, Patrick
RT   "Neurotrophin-3 production promotes human neuroblastoma cell survival
RT   by inhibiting TrkC-induced apoptosis.";
RL   J. Clin. Invest. 120:850-858(2010).
//
RX   PubMed=18923523; DOI=10.1038/nature07398;
RA   Janoueix-Lerosey, Isabelle
RA   Lequin, Delphine
RA   Brugieres, Laurence
RA   Ribeiro, Agnes
RA   de Pontual, Loic
RA   Combaret, Valerie
RA   Raynal, Virginie
RA   Puisieux, Alain
RA   Schleiermacher, Gudrun
RA   Pierron, Gaelle
RA   Valteau-Couanet, Dominique
RA   Frebourg, Thierry
RA   Michon, Jean
RA   Lyonnet, Stanislas
RA   Amiel, Jeanne
RA   Delattre, Olivier
RT   "Somatic and germline activating mutations of the ALK kinase receptor
RT   in neuroblastoma.";
RL   Nature 455:967-970(2008).
//