ID   OUMS-21 [1993]
AC   CVCL_9131
SY   Okayama University Medical School-21
DR   Wikidata; Q54936766
RX   DOI=10.1007/978-1-4612-0411-4_32;
RX   PubMed=7683277;
RX   PubMed=14966424;
CC   Population: Japanese.
CC   Senescence: SV40-transformed but with a finite life span.
CC   Doubling time: 29.4 hours (PubMed=7683277).
CC   Transfected with: UniProtKB; P00552; Transposon Tn5 neo.
CC   Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40) [Note=pSV3-neo].
CC   Caution: Two cell lines named OUMS-21 have been created at Okayama University Medical School, one in 1972 from the peripheral blood of a normal adult donor (Cellosaurus=CVCL_A7SC) and one in 1993 from the SV40-transformed liver of a fetus (Cellosaurus=CVCL_9131).
CC   Derived from site: In situ; Fetal liver; UBERON=UBERON_0002107.
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
OI   CVCL_9132 ! OUMS-22 [1993]
SX   Sex unspecified
AG   18FW
CA   Finite cell line
DT   Created: 06-06-12; Last updated: 05-10-23; Version: 20
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RX   DOI=10.1007/978-1-4612-0411-4_32;
RA   Namba M., Kano Y., Bai L.-Y., Mihara K., Miyazaki M.;
RT   "Establishment and characterization of SV40 t-antigen immortalized
RT   human liver cells.";
RL   (In) Neoplastic transformation in human cell system. Mechanism of carcinogenesis; Rhim J.S., Dritschilo A. (eds.); pp.323-332; Humana Press; New York (1990).
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RX   PubMed=7683277; DOI=10.1006/excr.1993.1116;
RA   Miyazaki M., Mihara K., Bai L.-Y., Kano Y., Tsuboi S., Endo A.,
RA   Seshimo K., Yoshioka T., Namba M.;
RT   "Immortalization of epithelial-like cells from human liver tissue with
RT   SV40 T-antigen gene.";
RL   Exp. Cell Res. 206:27-35(1993).
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RX   PubMed=14966424; DOI=10.1097/01.TP.0000110292.73873.25;
RA   Maruyama M., Kobayashi N., Westerman K.A., Sakaguchi M., Allain J.-E.,
RA   Totsugawa T., Okitsu T., Fukazawa T., Weber A., Stolz D.B.,
RA   Leboulch P., Tanaka N.;
RT   "Establishment of a highly differentiated immortalized human
RT   cholangiocyte cell line with SV40T and hTERT.";
RL   Transplantation 77:446-451(2004).
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