ID   OUMS-29
AC   CVCL_9130
SY   Okayama University Medical School-29
DR   Wikidata; Q54936777
RX   DOI=10.11418/jtca1981.16.3_173;
RX   PubMed=10670627;
RX   PubMed=11513080;
RX   PubMed=11575821;
RX   PubMed=11605014;
RX   PubMed=15375599;
CC   Population: Japanese.
CC   Genetic integration: Method=Transfection; Gene=UniProtKB; P03070; SV40 large T antigen.
CC   Genetic integration: Method=Transfection; Gene=UniProtKB; P00552; Transposon Tn5 neo.
CC   Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40) (Note=pSV3-neo).
CC   Derived from site: In situ; Fetal liver; UBERON=UBERON_0002107.
CC   Cell type: Hepatocyte; CL=CL_0000182.
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Male
AG   21FW
CA   Transformed cell line
DT   Created: 06-06-12; Last updated: 10-09-24; Version: 15
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RX   DOI=10.11418/jtca1981.16.3_173;
RA   Mihara K., Miyazaki M., Fushimi K., Tsuji T., Inoue Y., Fukaya K.-i.,
RA   Ohashi R., Namba M.;
RT   "The p53 gene status and other cellular characteristics of human cell
RT   lines maintained in our laboratory.";
RL   Tissue Cult. Res. Commun. 16:173-178(1997).
//
RX   PubMed=10670627; DOI=10.1097/00007890-200001270-00002;
RA   Kobayashi N., Miyazaki M., Fukaya K.-i., Inoue Y., Sakaguchi M.,
RA   Uemura T., Noguchi H., Kondo A., Tanaka N., Namba M.;
RT   "Transplantation of highly differentiated immortalized human
RT   hepatocytes to treat acute liver failure.";
RL   Transplantation 69:202-207(2000).
//
RX   PubMed=11513080; DOI=10.1007/BF02577541;
RA   Fukaya K.-i., Asahi S., Nagamori S., Sakaguchi M., Gao C.,
RA   Miyazaki M., Namba M.;
RT   "Establishment of a human hepatocyte line (OUMS-29) having CYP 1A1 and
RT   1A2 activities from fetal liver tissue by transfection of SV40 LT.";
RL   In Vitro Cell. Dev. Biol. Anim. 37:266-269(2001).
//
RX   PubMed=11575821; DOI=10.1097/00002480-200109000-00016;
RA   Kobayashi N., Miyazaki M., Westerman K.A., Noguchi H., Sakaguchi M.,
RA   Totsugawa T., Watanabe T., Matsumura T., Fujiwara T., Leboulch P.,
RA   Tanaka N., Namba M.;
RT   "Construction of a differentiated human hepatocyte cell line
RT   expressing the herpes simplex virus-thymidine kinase gene.";
RL   ASAIO J. 47:476-480(2001).
//
RX   PubMed=11605014; DOI=10.3892/ijmm.8.5.481;
RA   Inoue Y., Miyazaki M., Tsuji T., Sakaguchi M., Fukaya K., Huh N.-H.,
RA   Namba M.;
RT   "Reactivation of liver-specific gene expression in an immortalized
RT   human hepatocyte cell line by introduction of the human HNF4alpha2
RT   gene.";
RL   Int. J. Mol. Med. 8:481-487(2001).
//
RX   PubMed=15375599; DOI=10.3892/ijmm.14.4.663;
RA   Akiyama I., Tomiyama K., Sakaguchi M., Takaishi M., Mori M.,
RA   Hosokawa M., Nagamori S., Shimizu N., Huh N.-H., Miyazaki M.;
RT   "Expression of CYP3A4 by an immortalized human hepatocyte line in a
RT   three-dimensional culture using a radial-flow bioreactor.";
RL   Int. J. Mol. Med. 14:663-668(2004).
//