ID   DT40-ITRP1(-/-)-ITPR2(-/-)
AC   CVCL_8B31
SY   IP3R type1^(-)/2^(-) DT40
DR   CLO; CLO_0051501
DR   RCB; RCB1717
DR   Wikidata; Q54831487
RX   PubMed=9214625;
CC   Group: Bird cell line.
CC   Knockout cell: Method=Targeted integration; CGNC; 49305; ITPR1.
CC   Knockout cell: Method=Targeted integration; CGNC; 10502; ITPR2.
CC   Transformant: NCBI_TaxID; 11864; Avian leukosis virus (ALV).
CC   Cell type: B-cell; CL=CL_0000236.
CC   Breed/subspecies: Hy-Line SC.
DI   NCIt; C134556; Chicken bursal lymphoma
OX   NCBI_TaxID=9031; ! Gallus gallus (Chicken)
HI   CVCL_0249 ! DT40
SX   Female
AG   1D
CA   Cancer cell line
DT   Created: 23-02-16; Last updated: 10-09-24; Version: 11
//
RX   PubMed=9214625; DOI=10.1093/emboj/16.11.3078; PMCID=PMC1169926;
RA   Sugawara, Hitoshi
RA   Kurosaki, Mari
RA   Takata, Minoru
RA   Kurosaki, Tomohiro
RT   "Genetic evidence for involvement of type 1, type 2 and type 3
RT   inositol 1,4,5-trisphosphate receptors in signal transduction through
RT   the B-cell antigen receptor.";
RL   EMBO J. 16:3078-3088(1997).
//