ID SJNB-7 AC CVCL_8824 AS CVCL_1449 SY SJ-NB-7; SJNB7; NB7; NB7-DH; NCG; SJ-NCG DR BTO; BTO_0003439 DR CLO; CLO_0037090 DR ArrayExpress; E-MTAB-783 DR ArrayExpress; E-MTAB-3610 DR BioGRID_ORCS_Cell_line; 952 DR cancercelllines; CVCL_8824 DR Cell_Model_Passport; SIDM00156 DR ChEMBL-Cells; CHEMBL3308158 DR ChEMBL-Targets; CHEMBL2366345 DR Cosmic; 688083 DR Cosmic; 801748 DR Cosmic; 947717 DR Cosmic; 949174 DR Cosmic; 1037337 DR Cosmic; 1099134 DR Cosmic; 1153798 DR Cosmic; 2131587 DR Cosmic-CLP; 949174 DR DepMap; ACH-002285 DR EGA; EGAS00001000978 DR GDSC; 949174 DR GEO; GSM314025 DR GEO; GSM333812 DR GEO; GSM1670155 DR IARC_TP53; 27180 DR LINCS_LDP; LCL-1997 DR PharmacoDB; NB7_994_2019 DR PRIDE; PXD030304 DR Progenetix; CVCL_8824 DR PubChem_Cell_line; CVCL_8824 DR Wikidata; Q54953579 RX DOI=10.1007/0-306-46872-7_2; RX PubMed=6171342; RX PubMed=8516298; RX PubMed=10935473; RX PubMed=15892104; RX PubMed=18923524; RX PubMed=20164919; RX PubMed=27397505; RX PubMed=30894373; RX PubMed=30971826; RX PubMed=35839778; CC Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE). CC Part of: COSMIC cell lines project. CC Population: Caucasian. CC Microsatellite instability: Stable (MSS) (Sanger). CC Sequence variation: Mutation; HGNC; HGNC:11998; TP53; Simple; p.Pro278Leu (c.833C>T); ClinVar=VCV000232497; Zygosity=Heterozygous (Cosmic-CLP=949174; DepMap=ACH-002285). CC Omics: Genomics; DNA methylation analysis. CC Omics: Genomics; Whole exome sequencing. CC Omics: Phenotyping; CRISPR screening. CC Omics: Phenotyping; Drug screening. CC Omics: Proteomics; Quantitative. CC Omics: Transcriptomics; Microarray. CC Omics: Variations; Array-based CGH. CC Omics: Variations; SNP array analysis. CC Genome ancestry: African=0.35%; Native American=0%; East Asian, North=0%; East Asian, South=0%; South Asian=0%; European, North=68.16%; European, South=31.49% (PubMed=30894373). ST Source(s): Cosmic-CLP=949174 ST Amelogenin: X,Y ST CSF1PO: 11,13 ST D13S317: 8,13 ST D16S539: 8,11 ST D5S818: 11,12 ST D7S820: 10,12 ST TH01: 9.3 ST TPOX: 11 ST vWA: 17,19 DI NCIt; C3270; Neuroblastoma DI ORDO; Orphanet_635; Neuroblastoma OX NCBI_TaxID=9606; ! Homo sapiens (Human) SX Male AG 7M CA Cancer cell line DT Created: 06-06-12; Last updated: 10-04-25; Version: 37 // RX PubMed=8516298; DOI=10.1073/pnas.90.12.5539; PMCID=PMC46756; RA Johnson, Maureen Riordan RA Look, Alfred Thomas RA DeClue, Jeffrey E. RA Valentine, Marcus B. RA Lowy, Douglas Ronald RT "Inactivation of the NF1 gene in human melanoma and neuroblastoma cell RT lines without impaired regulation of GTP.Ras."; RL Proc. Natl. Acad. Sci. U.S.A. 90:5539-5543(1993). // RX PubMed=35839778; DOI=10.1016/j.ccell.2022.06.010; PMCID=PMC9387775; RA Goncalves, Emanuel RA Poulos, Rebecca C. RA Cai, Zhao-Xiang RA Barthorpe, Syd RA Manda, Srikanth S. RA Lucas, Natasha RA Beck, Alexandra RA Bucio-Noble, Daniel RA Dausmann, Michael RA Hall, Caitlin RA Hecker, Michael RA Koh, Jennifer RA Lightfoot, Howard RA Mahboob, Sadia RA Mali, Iman RA Morris, James RA Richardson, Laura RA Seneviratne, Akila J. RA Shepherd, Rebecca RA Sykes, Erin RA Thomas, Frances RA Valentini, Sara RA Williams, Steven G. RA Wu, Yang-Xiu RA Xavier, Dylan RA MacKenzie, Karen L. RA Hains, Peter G. RA Tully, Brett RA Robinson, Phillip James RA Zhong, Qing RA Garnett, Mathew J. RA Reddel, Roger Robert RT "Pan-cancer proteomic map of 949 human cell lines."; RL Cancer Cell 40:835-849.e8(2022). // RX PubMed=10935473; DOI=10.1038/sj.neo.7900010; PMCID=PMC1716055; RA Kong, Xiao-Tang RA Valentine, Virginia A. RA Rowe, Susan T. RA Valentine, Marcus B. RA Ragsdale, Susan T. RA Jones, Bart G. RA Wilkinson, Deborah A. RA Brodeur, Garrett M. RA Cohn, Susan Lerner RA Look, Alfred Thomas RT "Lack of homozygously inactivated p73 in single-copy MYCN primary RT neuroblastomas and neuroblastoma cell lines."; RL Neoplasia 1:80-89(1999). // RX PubMed=30971826; DOI=10.1038/s41586-019-1103-9; RA Behan, Fiona M. RA Iorio, Francesco RA Picco, Gabriele RA Goncalves, Emanuel RA Beaver, Charlotte M. RA Migliardi, Giorgia RA Santos, Rita RA Rao, Yanhua RA Sassi, Francesco RA Pinnelli, Marika RA Ansari, Rizwan RA Harper, Sarah RA Jackson, David Adam RA McRae, Rebecca RA Pooley, Rachel RA Wilkinson, Piers RA van der Meer, Dieudonne J. RA Dow, David RA Buser-Doepner, Carolyn A. RA Bertotti, Andrea RA Trusolino, Livio RA Stronach, Euan Alexander RA Saez-Rodriguez, Julio RA Yusa, Kosuke RA Garnett, Mathew J. RT "Prioritization of cancer therapeutic targets using CRISPR-Cas9 RT screens."; RL Nature 568:511-516(2019). // RX PubMed=27397505; DOI=10.1016/j.cell.2016.06.017; PMCID=PMC4967469; RA Iorio, Francesco RA Knijnenburg, Theo A. RA Vis, Daniel J. RA Bignell, Graham Robert RA Menden, Michael Patrick RA Schubert, Michael RA Aben, Nanne RA Goncalves, Emanuel RA Barthorpe, Syd RA Lightfoot, Howard RA Cokelaer, Thomas RA Greninger, Patricia RA van Dyk, Ewald RA Chang, Han RA de Silva, Heshani RA Heyn, Holger RA Deng, Xian-Ming RA Egan, Regina K. RA Liu, Qing-Song RA Mironenko, Tatiana RA Mitropoulos, Xeni RA Richardson, Laura RA Wang, Jin-Hua RA Zhang, Ting-Hu RA Moran, Sebastian RA Sayols, Sergi RA Soleimani, Maryam RA Tamborero, David RA Lopez-Bigas, Nuria RA Ross-Macdonald, Petra RA Esteller, Manel RA Gray, Nathanael S. RA Haber, Daniel Arie RA Stratton, Michael Rudolf RA Benes, Cyril Henri RA Wessels, Lodewyk F.A. RA Saez-Rodriguez, Julio RA McDermott, Ultan RA Garnett, Mathew J. RT "A landscape of pharmacogenomic interactions in cancer."; RL Cell 166:740-754(2016). // RX DOI=10.1007/0-306-46872-7_2; RA Thiele, Carol Jeanne RT "Neuroblastoma."; RL (In book chapter) Human cell culture. Vol. 1. Cancer cell lines part 1; Masters, John R.W. & Palsson, Bernhard Orn (eds.); pp.21-53; Kluwer Academic Publishers; New York; USA (1999). // RX PubMed=18923524; DOI=10.1038/nature07399; RA Chen, Yu-Yan RA Takita, Junko RA Choi, Young Lim RA Kato, Motohiro RA Ohira, Miki RA Sanada, Masashi RA Wang, Li-Li RA Soda, Manabu RA Kikuchi, Akira RA Igarashi, Takashi RA Nakagawara, Akira RA Hayashi, Yasuhide RA Mano, Hiroyuki RA Ogawa, Seishi RT "Oncogenic mutations of ALK kinase in neuroblastoma."; RL Nature 455:971-974(2008). // RX PubMed=15892104; DOI=10.1002/gcc.20198; RA Mosse, Yael P. RA Greshock, Joel RA Margolin, Adam A. RA Naylor, Tara RA Cole, Kristina A. RA Khazi, Deepa RA Hii, George RA Winter, Cynthia RA Shahzad, Syed RA Asziz, Muhammad Usman RA Biegel, Jaclyn A. RA Weber, Barbara L. RA Maris, John Matthew RT "High-resolution detection and mapping of genomic DNA alterations in RT neuroblastoma."; RL Genes Chromosomes Cancer 43:390-403(2005). // RX PubMed=6171342; RA Brodeur, Garrett M. RA Green, Alexander A. RA Hayes, F. Ann RA Williams, Kenna J. RA Williams, Dorothy L. RA Tsiatis, Anastasios Athanasios RT "Cytogenetic features of human neuroblastomas and cell lines."; RL Cancer Res. 41:4678-4686(1981). // RX PubMed=30894373; DOI=10.1158/0008-5472.CAN-18-2747; PMCID=PMC6445675; RA Dutil, Julie RA Chen, Zhi-Hua RA Monteiro, Alvaro N.A. RA Teer, Jamie K. RA Eschrich, Steven A. RT "An interactive resource to probe genetic diversity and estimated RT ancestry in cancer cell lines."; RL Cancer Res. 79:1263-1273(2019). // RX PubMed=20164919; DOI=10.1038/nature08768; PMCID=PMC3145113; RA Bignell, Graham Robert RA Greenman, Christopher D. RA Davies, Helen R. RA Butler, Adam P. RA Edkins, Sarah RA Andrews, Jenny M. RA Buck, Gemma RA Chen, Lina RA Beare, David RA Latimer, Calli RA Widaa, Sara RA Hinton, Jonathan RA Fahey, Ciara RA Fu, Bei-Yuan RA Swamy, Sajani RA Dalgliesh, Gillian L. RA Teh, Bin Tean RA Deloukas, Panos RA Yang, Feng-Tang RA Campbell, Peter J. RA Futreal, P. Andrew RA Stratton, Michael Rudolf RT "Signatures of mutation and selection in the cancer genome."; RL Nature 463:893-898(2010). //