AC   CVCL_8706
SY   Hone-1; HONE1; Hone1
DR   BTO; BTO:0006136
DR   BioSample; SAMN03472391
DR   cancercelllines; CVCL_8706
DR   ChEMBL-Cells; CHEMBL3308670
DR   ChEMBL-Targets; CHEMBL614830
DR   Cosmic; 755506
DR   Cosmic; 944908
DR   Cosmic; 1017620
DR   Cosmic; 1300998
DR   Cosmic; 1322948
DR   Cosmic; 2366881
DR   GEO; GSM375844
DR   GEO; GSM378801
DR   GEO; GSM378802
DR   Progenetix; CVCL_8706
DR   PubChem_Cell_line; CVCL_8706
DR   TOKU-E; 3587
DR   Wikidata; Q54890147
RX   CelloPub=CLPUB00484;
RX   PubMed=2556716;
RX   PubMed=12097280;
RX   PubMed=24991015;
RX   PubMed=25877200;
CC   Problematic cell line: Seems to bear part of the HeLa genomic sequence; may be a derivative of HeLa and another cell of unknown origin (PubMed=24991015).
CC   Registration: International Cell Line Authentication Committee, Register of Misidentified Cell Lines; ICLAC-00496.
CC   Transformant: NCBI_TaxID; 10376; Epstein-Barr virus (EBV).
CC   Omics: Transcriptome analysis by RNAseq.
CC   Misspelling: HOME-1; Note=Occasionally.
ST   Source(s): PubMed=25877200
ST   Amelogenin: X
ST   CSF1PO: 10,11
ST   D13S317: 10,12
ST   D16S539: 9,10,11
ST   D18S51: 13,16
ST   D21S11: 27,30
ST   D3S1358: 15,18
ST   D5S818: 11,12
ST   D7S820: 10,12
ST   D8S1179: 12
ST   FGA: 18,21
ST   Penta D: 9,12
ST   Penta E: 17,20
ST   TH01: 6,9
ST   TPOX: 8,12
ST   vWA: 14,16
DI   NCIt; C3871; Nasopharyngeal carcinoma
DI   ORDO; Orphanet_150; Nasopharyngeal carcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Male
CA   Cancer cell line
DT   Created: 04-04-12; Last updated: 02-05-24; Version: 27
RX   CelloPub=CLPUB00484;
RA   Xu Z.-H., Sun W.-W., Hang J.-B., Gao B.-L., Hu J.-A.;
RT   "RNA-seq identified a novel functional MET fusion in head and neck
RT   cancer 5-8F cell line.";
RL   Int. J. Clin. Exp. Pathol. 9:8308-8317(2016).
RX   PubMed=2556716; DOI=10.1073/pnas.86.23.9524;
RA   Glaser R., Zhang H.-Y., Yao K.-T., Zhu H.-C., Wang F.-X., Li G.-Y.,
RA   Wen D.-S., Li Y.-P.;
RT   "Two epithelial tumor cell lines (HNE-1 and HONE-1) latently infected
RT   with Epstein-Barr virus that were derived from nasopharyngeal
RT   carcinomas.";
RL   Proc. Natl. Acad. Sci. U.S.A. 86:9524-9528(1989).
RX   PubMed=12097280;
RA   Chang J.-Y., Liu J.-F., Juang S.-H., Liu T.-W., Chen L.-T.;
RT   "Novel mutation of topoisomerase I in rendering cells resistant to
RT   camptothecin.";
RL   Cancer Res. 62:3716-3721(2002).
RX   PubMed=24991015; DOI=10.1128/JVI.01457-14;
RA   Strong M.J., Baddoo M., Nanbo A., Xu M., Puetter A., Lin Z.;
RT   "Comprehensive RNA-seq analysis reveals contamination of multiple
RT   nasopharyngeal carcinoma cell lines with HeLa cell genomes.";
RL   J. Virol. 88:10696-10704(2014).
RX   PubMed=25877200; DOI=10.1038/nature14397;
RA   Yu M., Selvaraj S.K., Liang-Chu M.M.Y., Aghajani S., Busse M.,
RA   Yuan J., Lee G., Peale F.V., Klijn C., Bourgon R., Kaminker J.S.,
RA   Neve R.M.;
RT   "A resource for cell line authentication, annotation and quality
RT   control.";
RL   Nature 520:307-311(2015).