ID   AR-EcoScreen
AC   CVCL_8544
DR   JCRB; JCRB1328
DR   Wikidata; Q54750350
RX   PubMed=15110108;
RX   PubMed=15713541;
WW   https://www.oecd.org/env/ehs/testing/Doc-id-381084-Draft-TG-AR-STTA-clean.pdf
CC   Biotechnology: Used in the AR STTA bioassay for the rapid evaluation of in vitro androgen receptor transcriptional activation.
CC   Characteristics: The luciferase reporter gene is under the control of a construct bearing four tandem repeats of a prostate C3 gene androgen-responsive element driven by a minimal heat shock protein promoter.
CC   Transfected with: HGNC; 644; AR.
CC   Transfected with: UniProtKB; P27652; Renilla-type luciferase.
CC   Derived from site: In situ; Ovary; UBERON=UBERON_0000992.
CC   Cell type: Epithelial cell of ovary; CL=CL_2000064.
OX   NCBI_TaxID=10029; ! Cricetulus griseus (Chinese hamster)
HI   CVCL_0214 ! CHO-K1
SX   Female
AG   Adult
CA   Spontaneously immortalized cell line
DT   Created: 04-04-12; Last updated: 30-01-24; Version: 10
//
RX   PubMed=15110108; DOI=10.1016/j.fct.2004.02.011;
RA   Satoh K., Ohyama K., Aoki N., Iida M., Nagai F.;
RT   "Study on anti-androgenic effects of bisphenol a diglycidyl ether
RT   (BADGE), bisphenol F diglycidyl ether (BFDGE) and their derivatives
RT   using cells stably transfected with human androgen receptor,
RT   AR-EcoScreen.";
RL   Food Chem. Toxicol. 42:983-993(2004).
//
RX   PubMed=15713541; DOI=10.1016/j.tiv.2004.10.008;
RA   Araki N., Ohno K., Takeyoshi M., Iida M.;
RT   "Evaluation of a rapid in vitro androgen receptor transcriptional
RT   activation assay using AR-EcoScreen cells.";
RL   Toxicol. In Vitro 19:335-352(2005).
//