ID   OU-AML-2
AC   CVCL_8392
DR   BioSample; SAMN03151868
DR   Wikidata; Q54936739
RX   PubMed=10027306;
RX   PubMed=12592342;
RX   PubMed=20143388;
WW   https://iclac.org/wp-content/uploads/Cross-Contaminations_v13_distribution.xlsx
CC   Problematic cell line: Contaminated. Shown to be a OCI-AML-2 derivative (PubMed=12592342; PubMed=20143388).
CC   Registration: International Cell Line Authentication Committee, Register of Misidentified Cell Lines; ICLAC-00248.
CC   Population: Caucasian.
CC   Sequence variation: Gene fusion; HGNC; 7137; AFDN + HGNC; 7132; KMT2A; Name(s)=KMT2A-AFDN, MLL-MLLT4, MLL-AF6 (from parent cell line).
CC   Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
DI   NCIt; C9154; Adult acute myeloid leukemia
DI   NCIt; C132105; Acute myeloid leukemia with t(6;11)(q27;q23) KMT2A-MLLT4
DI   ORDO; Orphanet_519; Acute myeloid leukemia
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_1619 ! OCI-AML-2
SX   Male
AG   65Y
CA   Cancer cell line
DT   Created: 04-04-12; Last updated: 02-05-24; Version: 25
//
RX   PubMed=10027306; DOI=10.1038/sj.bjc.6690064; PMCID=PMC2362446;
RA   Zheng A.-P., Castren K., Saily M., Savolainen E.-R., Koistinen P.O.,
RA   Vahakangas K.H.;
RT   "p53 status of newly established acute myeloid leukaemia cell lines.";
RL   Br. J. Cancer 79:407-415(1999).
//
RX   PubMed=12592342; DOI=10.1038/sj.leu.2402799;
RA   Drexler H.G., Dirks W.G., Matsuo Y., MacLeod R.A.F.;
RT   "False leukemia-lymphoma cell lines: an update on over 500 cell
RT   lines.";
RL   Leukemia 17:416-426(2003).
//
RX   PubMed=20143388; DOI=10.1002/ijc.25242;
RA   Capes-Davis A., Theodosopoulos G., Atkin I., Drexler H.G., Kohara A.,
RA   MacLeod R.A.F., Masters J.R.W., Nakamura Y., Reid Y.A., Reddel R.R.,
RA   Freshney R.I.;
RT   "Check your cultures! A list of cross-contaminated or misidentified
RT   cell lines.";
RL   Int. J. Cancer 127:1-8(2010).
//