ID   HuL-1
AC   CVCL_8357
SY   HUL-1; Human Liver-1
DR   BioSample; SAMN03151718
DR   BioSample; SAMN03472367
DR   JCRB; NIHS0231
DR   RCB; RCB0077
DR   RCB; RCB1457
DR   Wikidata; Q54896866
RX   CelloPub=CLPUB00527;
RX   PubMed=2836073;
RX   PubMed=3986962;
RX   PubMed=7206264;
RX   PubMed=15767549;
RX   PubMed=20143388;
WW   Info; ICLAC; -; https://iclac.org/wp-content/uploads/Cross-Contaminations_v13_distribution.xlsx
WW   Info; JCRB; -; https://cellbank.nibiohn.go.jp/legacy/cellbank/qualitycontrol/identification/summary.htm
CC   Problematic cell line: Contaminated. Shown to be a HeLa derivative (PubMed=20143388). Originally thought to originate from a 4 month old male fetal liver.
CC   Part of: JFCR45 cancer cell line panel.
CC   Registration: International Cell Line Authentication Committee, Register of Misidentified Cell Lines; ICLAC-00318.
CC   Population: African American.
CC   Transformant: NCBI_TaxID; 333761; Human papillomavirus type 18 (HPV18).
CC   Omics: Transcriptomics; Microarray.
CC   Discontinued: JCRB; NIHS0231; true.
CC   Discontinued: RCB; RCB0077; true.
CC   Discontinued: RCB; RCB1457; true.
CC   Derived from site: In situ; Uterus, cervix; UBERON=UBERON_0000002.
ST   Source(s): JCRB=NIHS0231; RCB=RCB0077
ST   Amelogenin: X
ST   CSF1PO: 9,10
ST   D13S317: 12,13.3
ST   D16S539: 10
ST   D5S818: 11,12
ST   D7S820: 12
ST   TH01: 7
ST   TPOX: 8,12
ST   vWA: 16,18
DI   NCIt; C27677; Human papillomavirus-related endocervical adenocarcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_0030 ! HeLa
SX   Female
AG   30Y6M
CA   Cancer cell line
DT   Created: 04-04-12; Last updated: 10-04-25; Version: 29
CH   CVCL_WH70 ! HuL-1.P3
//
RX   PubMed=7206264;
RA   Katsuta, Hajim
RA   Takaoka, Toshiko
RA   Huh, Nam-Ho
RT   "Establishment of tissue culture cell strains from normal fetal human
RT   liver and kidney.";
RL   Jpn. J. Exp. Med. 50:329-337(1980).
//
RX   PubMed=20143388; DOI=10.1002/ijc.25242;
RA   Capes-Davis, Amanda
RA   Theodosopoulos, George
RA   Atkin, Isobel
RA   Drexler, Hans Gunther
RA   Kohara, Arihiro
RA   MacLeod, Roderick A.F.
RA   Masters, John R.W.
RA   Nakamura, Yukio
RA   Reid, Yvonne A.
RA   Reddel, Roger Robert
RA   Freshney, Robert Ian
RT   "Check your cultures! A list of cross-contaminated or misidentified
RT   cell lines.";
RL   Int. J. Cancer 127:1-8(2010).
//
RX   PubMed=3986962; DOI=10.1093/carcin/6.4.549;
RA   Watatani, Masahiro
RA   Ikenaga, Mituo
RA   Hatanaka, Toshihiro
RA   Kinuta, Masakatsu
RA   Takai, Shin-ichiro
RA   Mori, Takesada
RA   Kondo, Sohei
RT   "Analysis of N-methyl-N'-nitro-N-nitrosoguanidine (MNNG)-induced DNA
RT   damage in tumor cell strains from Japanese patients and demonstration
RT   of MNNG hypersensitivity of Mer xenografts in athymic nude mice.";
RL   Carcinogenesis 6:549-553(1985).
//
RX   PubMed=15767549; DOI=10.1158/1535-7163.MCT-04-0234;
RA   Nakatsu, Noriyuki
RA   Yoshida, Yoko
RA   Yamazaki, Kanami
RA   Nakamura, Tomoki
RA   Dan, Shingo
RA   Fukui, Yasuhisa
RA   Yamori, Takao
RT   "Chemosensitivity profile of cancer cell lines and identification of
RT   genes determining chemosensitivity by an integrated bioinformatical
RT   approach using cDNA arrays.";
RL   Mol. Cancer Ther. 4:399-412(2005).
//
RX   PubMed=2836073; DOI=10.1247/csf.13.1;
RA   Sorimachi, Kenji
RA   Hayashi, Takayuki
RA   Takaoka, Toshiko
RA   Niwa, Akira
RA   Yasumura, Yosihiro
RT   "Requirement of serum pretreatment for induction of alkaline
RT   phosphatase activity with prednisolone, butyrate, dibutyryl cyclic
RT   adenosine monophosphate and NaCl in human liver cells continuously
RT   cultured in serum-free medium.";
RL   Cell Struct. Funct. 13:1-11(1988).
//
RX   CelloPub=CLPUB00527;
RA   Manaka, Ken-ishi
RA   Nonaka, Noritaka
RA   Yamada, Takashi
RA   Hirai, Hidematsu
RT   "Monoclonal antibodies against large-cell carcinoma of the lung.";
RL   Dokkyo J. Med. Sci. 12:31-41(1985).
//