ID   HuL-1
AC   CVCL_8357
SY   HUL-1; Human Liver-1
DR   BioSample; SAMN03151718
DR   BioSample; SAMN03472367
DR   RCB; RCB0077
DR   RCB; RCB1457
DR   Wikidata; Q54896866
RX   CelloPub=CLPUB00527;
RX   PubMed=2836073;
RX   PubMed=3986962;
RX   PubMed=7206264;
RX   PubMed=15767549;
RX   PubMed=20143388;
CC   Problematic cell line: Contaminated. Shown to be a HeLa derivative (PubMed=20143388). Originally thought to originate from a 4 month old male fetal liver.
CC   Part of: JFCR45 cancer cell line panel.
CC   Registration: International Cell Line Authentication Committee, Register of Misidentified Cell Lines; ICLAC-00318.
CC   Population: African American.
CC   Transformant: NCBI_TaxID; 333761; Human papillomavirus type 18 (HPV18).
CC   Omics: Transcriptome analysis by microarray.
CC   Discontinued: JCRB; NIHS0231; true.
CC   Discontinued: RCB; RCB0077; true.
CC   Discontinued: RCB; RCB1457; true.
CC   Derived from site: In situ; Uterus, cervix; UBERON=UBERON_0000002.
ST   Source(s): JCRB=NIHS0231; RCB=RCB0077
ST   Amelogenin: X
ST   CSF1PO: 9,10
ST   D13S317: 12,13.3
ST   D16S539: 10
ST   D5S818: 11,12
ST   D7S820: 12
ST   TH01: 7
ST   TPOX: 8,12
ST   vWA: 16,18
DI   NCIt; C27677; Human papillomavirus-related cervical adenocarcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_0030 ! HeLa
SX   Female
AG   30Y6M
CA   Cancer cell line
DT   Created: 04-04-12; Last updated: 02-05-24; Version: 28
RX   CelloPub=CLPUB00527;
RA   Manaka K.-i., Nonaka N., Yamada T., Hirai H.;
RT   "Monoclonal antibodies against large-cell carcinoma of the lung.";
RL   Dokkyo J. Med. Sci. 12:31-41(1985).
RX   PubMed=2836073; DOI=10.1247/csf.13.1;
RA   Sorimachi K., Hayashi T., Takaoka T., Niwa A., Yasumura Y.;
RT   "Requirement of serum pretreatment for induction of alkaline
RT   phosphatase activity with prednisolone, butyrate, dibutyryl cyclic
RT   adenosine monophosphate and NaCl in human liver cells continuously
RT   cultured in serum-free medium.";
RL   Cell Struct. Funct. 13:1-11(1988).
RX   PubMed=3986962; DOI=10.1093/carcin/6.4.549;
RA   Watatani M., Ikenaga M., Hatanaka T., Kinuta M., Takai S.-i., Mori T.,
RA   Kondo S.;
RT   "Analysis of N-methyl-N'-nitro-N-nitrosoguanidine (MNNG)-induced DNA
RT   damage in tumor cell strains from Japanese patients and demonstration
RT   of MNNG hypersensitivity of Mer xenografts in athymic nude mice.";
RL   Carcinogenesis 6:549-553(1985).
RX   PubMed=7206264;
RA   Katsuta H., Takaoka T., Huh N.-H.;
RT   "Establishment of tissue culture cell strains from normal fetal human
RT   liver and kidney.";
RL   Jpn. J. Exp. Med. 50:329-337(1980).
RX   PubMed=15767549; DOI=10.1158/1535-7163.MCT-04-0234;
RA   Nakatsu N., Yoshida Y., Yamazaki K., Nakamura T., Dan S., Fukui Y.,
RA   Yamori T.;
RT   "Chemosensitivity profile of cancer cell lines and identification of
RT   genes determining chemosensitivity by an integrated bioinformatical
RT   approach using cDNA arrays.";
RL   Mol. Cancer Ther. 4:399-412(2005).
RX   PubMed=20143388; DOI=10.1002/ijc.25242;
RA   Capes-Davis A., Theodosopoulos G., Atkin I., Drexler H.G., Kohara A.,
RA   MacLeod R.A.F., Masters J.R.W., Nakamura Y., Reid Y.A., Reddel R.R.,
RA   Freshney R.I.;
RT   "Check your cultures! A list of cross-contaminated or misidentified
RT   cell lines.";
RL   Int. J. Cancer 127:1-8(2010).