ID   ATL-35T
AC   CVCL_8339
SY   ATL-35T(-); ATL35T
DR   RCB; RCB3555
DR   Wikidata; Q54751262
RX   PubMed=16242045;
RX   PubMed=16314839;
RX   PubMed=32210945;
CC   Population: Japanese.
CC   Characteristics: Lost its original IL2 dependency.
CC   Transformant: NCBI_TaxID; 11908; Human T-lymphotropic virus 1 (HTLV-1).
CC   Donor information: Established from a patient suffering from adult T-cell leukemia/lymphoma (ATLL).
CC   Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
CC   Cell type: T-cell; CL=CL_0000084.
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Sex unspecified
AG   Adult
CA   Transformed cell line
DT   Created: 04-04-12; Last updated: 29-06-23; Version: 14
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RX   PubMed=32210945; DOI=10.3389/fmicb.2020.00356; PMCID=PMC7067701;
RA   Maeda, Michiyuki
RA   Tanabe-Shibuya, Junko
RA   Miyazato, Paola
RA   Masutani, Hiroshi
RA   Yasunaga, Jun-ichirou
RA   Usami, Kazumasa
RA   Shimizu, Akira
RA   Matsuoka, Masao
RT   "IL-2/IL-2 receptor pathway plays a crucial role in the growth and
RT   malignant transformation of HTLV-1-infected T cells to develop adult
RT   T-cell leukemia.";
RL   Front. Microbiol. 11:356.1-356.17(2020).
//
RX   PubMed=16242045; DOI=10.1186/1742-4690-2-64; PMCID=PMC1289293;
RA   Taniguchi, Yuko
RA   Nosaka, Kisato
RA   Yasunaga, Jun-ichirou
RA   Maeda, Michiyuki
RA   Mueller, Nancy
RA   Okayama, Akihiko
RA   Matsuoka, Masao
RT   "Silencing of human T-cell leukemia virus type I gene transcription by
RT   epigenetic mechanisms.";
RL   Retrovirology 2:64.1-64.16(2005).
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RX   PubMed=16314839; DOI=10.1038/sj.onc.1209256;
RA   Ahsan, Mohammed Kaimul
RA   Masutani, Hiroshi
RA   Yamaguchi, Yoshimi
RA   Kim, Yong-Chul
RA   Nosaka, Kisato
RA   Matsuoka, Masao
RA   Nishinaka, Yumiko
RA   Maeda, Michiyuki
RA   Yodoi, Junji
RT   "Loss of interleukin-2-dependency in HTLV-I-infected T cells on gene
RT   silencing of thioredoxin-binding protein-2.";
RL   Oncogene 25:2181-2191(2006).
//