ID   KK47
AC   CVCL_8253
SY   KK-47
DR   BTO; BTO:0003552
DR   cancercelllines; CVCL_8253
DR   ChEMBL-Cells; CHEMBL3308615
DR   ChEMBL-Targets; CHEMBL614674
DR   Cosmic; 925824
DR   Cosmic; 2037949
DR   GEO; GSM136247
DR   GEO; GSM492492
DR   GEO; GSM1374600
DR   GEO; GSM1574547
DR   Progenetix; CVCL_8253
DR   PubChem_Cell_line; CVCL_8253
DR   TKG; TKG 0663
DR   Wikidata; Q54899980
RX   PubMed=470258;
RX   PubMed=604596;
RX   PubMed=1353119;
RX   PubMed=3708594;
RX   PubMed=6244232;
RX   PubMed=6620776;
RX   PubMed=24018021;
RX   PubMed=25997541;
RX   PubMed=29732388;
CC   Part of: BLA-40 bladder carcinoma cell line panel.
CC   Part of: UBC-40 urothelial bladder cancer cell line index.
CC   Population: Japanese.
CC   Doubling time: 23.5 hours (PubMed=470258); 27 hours (PubMed=1353119).
CC   Omics: CNV analysis.
CC   Omics: SNP array analysis.
CC   Omics: Transcriptome analysis by microarray.
CC   Derived from site: In situ; Urinary bladder; UBERON=UBERON_0001255.
ST   Source(s): TKG=TKG 0663
ST   Amelogenin: X
ST   CSF1PO: 9,10
ST   D13S317: 12,13.3
ST   D16S539: 9,10
ST   D5S818: 11,12,13
ST   D7S820: 8,12
ST   TH01: 7
ST   TPOX: 12
ST   vWA: 17,18
DI   NCIt; C4912; Bladder carcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Male
AG   50Y
CA   Cancer cell line
DT   Created: 04-04-12; Last updated: 02-05-24; Version: 26
//
RX   PubMed=470258; DOI=10.5980/jpnjurol1928.70.5_485;
RA   Hisazumi H., Kanokogi M., Nakajima K., Kobayashi T., Tsukahara K.,
RA   Naito K., Kuroda K., Matsubara F.;
RT   "Established cell line of urinary bladder carcinoma (KK-47): growth,
RT   heterotransplantation, microscopic structure and chromosome pattern.";
RL   Nihon Hinyokika Gakkai Zasshi 70:485-494(1979).
//
RX   PubMed=604596; DOI=10.5980/jpnjurol1928.68.11_1003;
RA   Taya T., Kobayashi T., Tsukahara K., Uchibayashi T., Naito K.,
RA   Hisazumi H., Kuroda K.;
RT   "In vitro culture of malignant tumor tissues from the human urinary
RT   tract.";
RL   Nihon Hinyokika Gakkai Zasshi 68:1003-1010(1977).
//
RX   PubMed=1353119; DOI=10.1016/S0022-5347(17)36624-7;
RA   Kimiya K., Naito S., Soejima T., Sakamoto N., Kotoh S., Kumazawa J.,
RA   Tsuruo T.;
RT   "Establishment and characterization of doxorubicin-resistant human
RT   bladder cancer cell line, KK47/ADM.";
RL   J. Urol. 148:441-445(1992).
//
RX   PubMed=3708594;
RA   Masters J.R.W., Hepburn P.J., Walker L., Highman W.J.,
RA   Trejdosiewicz L.K., Povey S., Parkar M., Hill B.T., Riddle P.N.,
RA   Franks L.M.;
RT   "Tissue culture model of transitional cell carcinoma: characterization
RT   of twenty-two human urothelial cell lines.";
RL   Cancer Res. 46:3630-3636(1986).
//
RX   PubMed=6244232;
RA   Williams R.D.;
RT   "Human urologic cancer cell lines.";
RL   Invest. Urol. 17:359-363(1980).
//
RX   PubMed=6620776; DOI=10.5980/jpnjurol1928.74.5_704;
RA   Koizumi H.;
RT   "Chemosensitivity of KK-47 bladder cancer cells and KN-41 renal cancer
RT   cells heterotransplanted in nude mice.";
RL   Nihon Hinyokika Gakkai Zasshi 74:704-718(1983).
//
RX   PubMed=24018021; DOI=10.1016/j.eururo.2013.08.052;
RA   Allory Y., Beukers W., Sagrera A., Flandez M., Marques M., Marquez M.,
RA   van der Keur K.A., Dyrskjot L., Lurkin I., Vermeij M., Carrato A.,
RA   Lloreta J., Lorente J.A., Carrillo-de-Santa-Pau E., Masius R.G.,
RA   Kogevinas M., Steyerberg E.W., van Tilborg A.A.G., Abas C.,
RA   Orntoft T.F., Zuiverloon T.C.M., Malats N., Zwarthoff E.C., Real F.X.;
RT   "Telomerase reverse transcriptase promoter mutations in bladder
RT   cancer: high frequency across stages, detection in urine, and lack of
RT   association with outcome.";
RL   Eur. Urol. 65:360-366(2014).
//
RX   PubMed=25997541; DOI=10.1186/s12864-015-1450-3;
RA   Earl J., Rico D., Carrillo-de-Santa-Pau E., Rodriguez-Santiago B.,
RA   Mendez-Pertuz M., Auer H., Gomez G., Grossman H.B., Pisano D.G.,
RA   Schulz W.A., Perez-Jurado L.A., Carrato A., Theodorescu D.,
RA   Chanock S.J., Valencia A., Real F.X.;
RT   "The UBC-40 Urothelial Bladder Cancer cell line index: a genomic
RT   resource for functional studies.";
RL   BMC Genomics 16:403.1-403.16(2015).
//
RX   PubMed=29732388; DOI=10.3233/BLC-180167;
RA   Zuiverloon T.C.M., de Jong F.C., Costello J.C., Theodorescu D.;
RT   "Systematic review: characteristics and preclinical uses of bladder
RT   cancer cell lines.";
RL   Bladder Cancer 4:169-183(2018).
//