ID   EPLC-32M1
AC   CVCL_8193
SY   EPLC 32M1; EPLC3-2M1; EPLC32M1; EPidermoid Lung Cancer-31M1
DR   ATCC; CRL-2182
DR   BioSample; SAMN03151690
DR   BioSample; SAMN03472559
DR   Wikidata; Q54832392
RX   PubMed=1845952;
RX   PubMed=2438285;
RX   PubMed=2473086;
RX   PubMed=2840315;
RX   PubMed=10508494;
RX   PubMed=20143388;
WW   Info; ICLAC; -; https://iclac.org/wp-content/uploads/Cross-Contaminations_v13_distribution.xlsx
CC   Problematic cell line: Contaminated. Shown to be a HeLa derivative (PubMed=10508494; PubMed=20143388). Originally thought to originate from a 68 year old male patient with lung squamous cell carcinoma.
CC   Registration: International Cell Line Authentication Committee, Register of Misidentified Cell Lines; ICLAC-00118.
CC   Population: African American.
CC   Transformant: NCBI_TaxID; 333761; Human papillomavirus type 18 (HPV18).
CC   Discontinued: ATCC; CRL-2182; true.
CC   Derived from site: In situ; Uterus, cervix; UBERON=UBERON_0000002.
ST   Source(s): ATCC=CRL-2182
ST   Amelogenin: X
ST   CSF1PO: 9,10
ST   D13S317: 13.3,14.3
ST   D16S539: 9,10
ST   D5S818: 11,12
ST   D7S820: 8,12
ST   TH01: 7
ST   TPOX: 8,12,13
ST   vWA: 17,18
DI   NCIt; C27677; Human papillomavirus-related endocervical adenocarcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_0030 ! HeLa
SX   Female
AG   30Y6M
CA   Cancer cell line
DT   Created: 04-04-12; Last updated: 10-04-25; Version: 26
//
RX   PubMed=10508494; DOI=10.1002/(SICI)1097-0215(19991112)83:4<555::AID-IJC19>3.0.CO;2-2;
RA   MacLeod, Roderick A.F.
RA   Dirks, Wilhelm Gerhard
RA   Matsuo, Yoshinobu
RA   Kaufmann, Maren
RA   Milch, Herbert
RA   Drexler, Hans Gunther
RT   "Widespread intraspecies cross-contamination of human tumor cell lines
RT   arising at source.";
RL   Int. J. Cancer 83:555-563(1999).
//
RX   PubMed=1845952; DOI=10.1002/1097-0142(19910201)67:3<619::AID-CNCR2820670317>3.0.CO;2-Y;
RA   Broers, Jos L.V.
RA   Mijnheere, Eddy P.
RA   Rot, Mirjam Klein
RA   Schaart, Gert
RA   Sijlmans, Alfred
RA   Boerman, Otto C.
RA   Ramaekers, Frans C.S.
RT   "Novel antigens characteristic of neuroendocrine malignancies.";
RL   Cancer 67:619-633(1991).
//
RX   PubMed=2840315; DOI=10.1111/j.1432-0436.1988.tb00806.x;
RA   Bepler, Gerold
RA   Koehler, Angelika
RA   Kiefer, Paul
RA   Havemann, Klaus
RA   Beisenherz, Karin
RA   Jaques, Gabriele
RA   Gropp, Claw
RA   Haeder, Maria
RT   "Characterization of the state of differentiation of six newly
RT   established human non-small-cell lung cancer cell lines.";
RL   Differentiation 37:158-171(1988).
//
RX   PubMed=20143388; DOI=10.1002/ijc.25242;
RA   Capes-Davis, Amanda
RA   Theodosopoulos, George
RA   Atkin, Isobel
RA   Drexler, Hans Gunther
RA   Kohara, Arihiro
RA   MacLeod, Roderick A.F.
RA   Masters, John R.W.
RA   Nakamura, Yukio
RA   Reid, Yvonne A.
RA   Reddel, Roger Robert
RA   Freshney, Robert Ian
RT   "Check your cultures! A list of cross-contaminated or misidentified
RT   cell lines.";
RL   Int. J. Cancer 127:1-8(2010).
//
RX   PubMed=2473086; DOI=10.1242/jcs.91.1.91;
RA   Broers, Jos L.V.
RA   Rot, Mirjam Klein
RA   Oostendorp, Tineke
RA   Bepler, Gerold
RA   de Leij, Lou F.M.H.
RA   Carney, Desmond Niall
RA   Vooijs, Gijsbert Peter
RA   Ramaekers, Frans C.S.
RT   "Spontaneous changes in intermediate filament protein expression
RT   patterns in lung cancer cell lines.";
RL   J. Cell Sci. 91:91-108(1988).
//
RX   PubMed=2438285; DOI=10.1007/BF00396382;
RA   Bepler, Gerold
RA   Jaques, Gabriele
RA   Koehler, Angelika
RA   Gropp, Claw
RA   Havemann, Klaus
RT   "Markers and characteristics of human SCLC cell lines. Neuroendocrine
RT   markers, classical tumor markers, and chromosomal characteristics of
RT   permanent human small cell lung cancer cell lines.";
RL   J. Cancer Res. Clin. Oncol. 113:253-259(1987).
//