ID   EPLC-32M1
AC   CVCL_8193
SY   EPLC 32M1; EPLC3-2M1; EPLC32M1; EPidermoid Lung Cancer-31M1
DR   ATCC; CRL-2182
DR   BioSample; SAMN03151690
DR   BioSample; SAMN03472559
DR   Wikidata; Q54832392
RX   PubMed=1845952;
RX   PubMed=2438285;
RX   PubMed=2473086;
RX   PubMed=2840315;
RX   PubMed=10508494;
RX   PubMed=20143388;
WW   https://iclac.org/wp-content/uploads/Cross-Contaminations_v13_distribution.xlsx
CC   Problematic cell line: Contaminated. Shown to be a HeLa derivative (PubMed=10508494; PubMed=20143388). Originally thought to originate from a 68 year old male patient with lung squamous cell carcinoma.
CC   Registration: International Cell Line Authentication Committee, Register of Misidentified Cell Lines; ICLAC-00118.
CC   Population: African American.
CC   Transformant: NCBI_TaxID; 333761; Human papillomavirus type 18 (HPV18).
CC   Discontinued: ATCC; CRL-2182; true.
CC   Derived from site: In situ; Uterus, cervix; UBERON=UBERON_0000002.
ST   Source(s): ATCC=CRL-2182
ST   Amelogenin: X
ST   CSF1PO: 9,10
ST   D13S317: 13.3,14.3
ST   D16S539: 9,10
ST   D5S818: 11,12
ST   D7S820: 8,12
ST   TH01: 7
ST   TPOX: 8,12,13
ST   vWA: 17,18
DI   NCIt; C27677; Human papillomavirus-related cervical adenocarcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_0030 ! HeLa
SX   Female
AG   30Y6M
CA   Cancer cell line
DT   Created: 04-04-12; Last updated: 02-05-24; Version: 25
//
RX   PubMed=1845952; DOI=10.1002/1097-0142(19910201)67:3<619::AID-CNCR2820670317>3.0.CO;2-Y;
RA   Broers J.L.V., Mijnheere E.P., Rot M.K., Schaart G., Sijlmans A.,
RA   Boerman O.C., Ramaekers F.C.S.;
RT   "Novel antigens characteristic of neuroendocrine malignancies.";
RL   Cancer 67:619-633(1991).
//
RX   PubMed=2438285; DOI=10.1007/BF00396382;
RA   Bepler G., Jaques G., Koehler A., Gropp C., Havemann K.;
RT   "Markers and characteristics of human SCLC cell lines. Neuroendocrine
RT   markers, classical tumor markers, and chromosomal characteristics of
RT   permanent human small cell lung cancer cell lines.";
RL   J. Cancer Res. Clin. Oncol. 113:253-259(1987).
//
RX   PubMed=2473086; DOI=10.1242/jcs.91.1.91;
RA   Broers J.L.V., Rot M.K., Oostendorp T., Bepler G., de Leij L.F.M.H.,
RA   Carney D.N., Vooijs G.P., Ramaekers F.C.S.;
RT   "Spontaneous changes in intermediate filament protein expression
RT   patterns in lung cancer cell lines.";
RL   J. Cell Sci. 91:91-108(1988).
//
RX   PubMed=2840315; DOI=10.1111/j.1432-0436.1988.tb00806.x;
RA   Bepler G., Koehler A., Kiefer P., Havemann K., Beisenherz K.,
RA   Jaques G., Gropp C., Haeder M.;
RT   "Characterization of the state of differentiation of six newly
RT   established human non-small-cell lung cancer cell lines.";
RL   Differentiation 37:158-171(1988).
//
RX   PubMed=10508494; DOI=10.1002/(SICI)1097-0215(19991112)83:4<555::AID-IJC19>3.0.CO;2-2;
RA   MacLeod R.A.F., Dirks W.G., Matsuo Y., Kaufmann M., Milch H.,
RA   Drexler H.G.;
RT   "Widespread intraspecies cross-contamination of human tumor cell lines
RT   arising at source.";
RL   Int. J. Cancer 83:555-563(1999).
//
RX   PubMed=20143388; DOI=10.1002/ijc.25242;
RA   Capes-Davis A., Theodosopoulos G., Atkin I., Drexler H.G., Kohara A.,
RA   MacLeod R.A.F., Masters J.R.W., Nakamura Y., Reid Y.A., Reddel R.R.,
RA   Freshney R.I.;
RT   "Check your cultures! A list of cross-contaminated or misidentified
RT   cell lines.";
RL   Int. J. Cancer 127:1-8(2010).
//