ID   TTC-642
AC   CVCL_8006
SY   TTC642
DR   BioSample; SAMN10989628
DR   cancercelllines; CVCL_8006
DR   Cell_Model_Passport; SIDM01456
DR   Cosmic; 801774
DR   Cosmic; 802053
DR   Cosmic; 2144785
DR   DepMap; ACH-001212
DR   GEO; GSM3145741
DR   Wikidata; Q54973252
RX   PubMed=9559292;
RX   PubMed=9920784;
RX   PubMed=10602515;
RX   PubMed=11921280;
RX   PubMed=12210830;
RX   PubMed=24418192;
RX   PubMed=31068700;
CC   Problematic cell line: Possibly misidentified. Presence of a Y chromosome in cell line that was thought to be of female origin (STR profile).
CC   Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
CC   From: Triche T.J.; Children's Hospital of Los Angeles; Los Angeles; USA.
CC   Karyotypic information: 45,XX,-22 (PubMed=9559292).
CC   Sequence variation: Mutation; HGNC; 11103; SMARCB1; Simple; p.Arg40Ter (c.118C>T); ClinVar=VCV000410698; Zygosity=Unspecified (PubMed=10602515; PubMed=11921280; DepMap).
CC   Omics: Deep exome analysis.
CC   Omics: SNP array analysis.
CC   Derived from site: Metastatic; Neck; UBERON=UBERON_0000974.
ST   Source(s): DepMap
ST   Amelogenin: X,Y
ST   CSF1PO: 10,12
ST   D13S317: 10,12
ST   D16S539: 9,11
ST   D18S51: 17,20
ST   D21S11: 31.2
ST   D3S1358: 17
ST   D5S818: 11,12
ST   D7S820: 11,12
ST   D8S1179: 12,15
ST   FGA: 21,23
ST   Penta D: 12,13
ST   Penta E: 9,17
ST   TH01: 9,9.3
ST   TPOX: 6,9
ST   vWA: 15,18
DI   NCIt; C6586; Extrarenal rhabdoid tumor
DI   ORDO; Orphanet_69077; Rhabdoid tumor
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Female
AG   5M
CA   Cancer cell line
DT   Created: 04-04-12; Last updated: 05-10-23; Version: 21
//
RX   PubMed=9559292; DOI=10.1097/00019606-199712000-00004;
RA   Suzuki A., Ohta S., Shimada M.;
RT   "Gene expression of malignant rhabdoid tumor cell lines by reverse
RT   transcriptase-polymerase chain reaction.";
RL   Diagn. Mol. Pathol. 6:326-332(1997).
//
RX   PubMed=9920784; DOI=10.1006/bbrc.1998.9968;
RA   Mori T., Fukuda Y., Kuroda H., Matsumura T., Ota S., Sugimoto T.,
RA   Nakamura Y., Inazawa J.;
RT   "Cloning and characterization of a novel Rab-family gene, Rab36,
RT   within the region at 22q11.2 that is homozygously deleted in malignant
RT   rhabdoid tumors.";
RL   Biochem. Biophys. Res. Commun. 254:594-600(1999).
//
RX   PubMed=10602515; DOI=10.1038/sj.onc.1203168;
RA   DeCristofaro M.F., Betz B.L., Wang W.-D., Weissman B.E.;
RT   "Alteration of hSNF5/INI1/BAF47 detected in rhabdoid cell lines and
RT   primary rhabdomyosarcomas but not Wilms' tumors.";
RL   Oncogene 18:7559-7565(1999).
//
RX   PubMed=11921280; DOI=10.1002/gcc.10052;
RA   Uno K., Takita J., Yokomori K., Tanaka Y., Ohta S., Shimada H.,
RA   Gilles F.H., Sugita K., Abe S., Sako M., Hashizume K., Hayashi Y.;
RT   "Aberrations of the hSNF5/INI1 gene are restricted to malignant
RT   rhabdoid tumors or atypical teratoid/rhabdoid tumors in pediatric
RT   solid tumors.";
RL   Genes Chromosomes Cancer 34:33-41(2002).
//
RX   PubMed=12210830; DOI=10.1002/jnr.10330;
RA   Yoshida S., Narita T., Taga T., Ohta S., Takeuchi Y.;
RT   "Malignant rhabdoid tumor shows incomplete neural characteristics as
RT   revealed by expression of SNARE complex.";
RL   J. Neurosci. Res. 69:642-652(2002).
//
RX   PubMed=24418192; DOI=10.1111/cas.12352;
RA   Takita J., Chen Y.-Y., Kato M., Ohki K., Sato Y., Ohta S., Sugita K.,
RA   Nishimura R., Hoshino N., Seki M., Sanada M., Oka A., Hayashi Y.,
RA   Ogawa S.;
RT   "Genome-wide approach to identify second gene targets for malignant
RT   rhabdoid tumors using high-density oligonucleotide microarrays.";
RL   Cancer Sci. 105:258-264(2014).
//
RX   PubMed=31068700; DOI=10.1038/s41586-019-1186-3;
RA   Ghandi M., Huang F.W., Jane-Valbuena J., Kryukov G.V., Lo C.C.,
RA   McDonald E.R. III, Barretina J.G., Gelfand E.T., Bielski C.M., Li H.-X.,
RA   Hu K., Andreev-Drakhlin A.Y., Kim J., Hess J.M., Haas B.J., Aguet F.,
RA   Weir B.A., Rothberg M.V., Paolella B.R., Lawrence M.S., Akbani R.,
RA   Lu Y.-L., Tiv H.L., Gokhale P.C., de Weck A., Mansour A.A., Oh C.,
RA   Shih J., Hadi K., Rosen Y., Bistline J., Venkatesan K., Reddy A.,
RA   Sonkin D., Liu M., Lehar J., Korn J.M., Porter D.A., Jones M.D.,
RA   Golji J., Caponigro G., Taylor J.E., Dunning C.M., Creech A.L.,
RA   Warren A.C., McFarland J.M., Zamanighomi M., Kauffmann A.,
RA   Stransky N., Imielinski M., Maruvka Y.E., Cherniack A.D.,
RA   Tsherniak A., Vazquez F., Jaffe J.D., Lane A.A., Weinstock D.M.,
RA   Johannessen C.M., Morrissey M.P., Stegmeier F., Schlegel R.,
RA   Hahn W.C., Getz G., Mills G.B., Boehm J.S., Golub T.R., Garraway L.A.,
RA   Sellers W.R.;
RT   "Next-generation characterization of the Cancer Cell Line
RT   Encyclopedia.";
RL   Nature 569:503-508(2019).
//