ID   STAV-FCS
AC   CVCL_7999
DR   BTO; BTO_0003756
DR   Wikidata; Q54956324
RX   PubMed=2790824;
RX   PubMed=7662316;
RX   PubMed=9310181;
RX   PubMed=23840376;
RX   PubMed=33567673;
CC   Characteristics: Grows with a fibroblast-like morphology in the presence of the FCS medium (PubMed=2790824).
CC   Doubling time: 90 hours (PubMed=23840376).
CC   Derived from site: In situ; Pleural effusion; UBERON=UBERON_0000175.
DI   NCIt; C45665; Pleural biphasic mesothelioma
DI   ORDO; Orphanet_50251; Pleural mesothelioma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
OI   CVCL_7998 ! STAV-AB
SX   Male
AG   60Y
CA   Cancer cell line
DT   Created: 04-04-12; Last updated: 19-12-24; Version: 14
//
RX   PubMed=2790824;
RA   Klominek J., Robert K.-H., Hjerpe A., Wickstrom B., Gahrton G.;
RT   "Serum-dependent growth patterns of two, newly established human
RT   mesothelioma cell lines.";
RL   Cancer Res. 49:6118-6122(1989).
//
RX   PubMed=7662316; DOI=10.1139/o95-007;
RA   Tzanakakis G.N., Karamanos N.K., Klominek J., Hjerpe A.;
RT   "Glycosaminoglycans from two human malignant mesothelioma cell lines:
RT   determination, distribution, and effect of platelet-derived growth
RT   factor on their synthesis.";
RL   Biochem. Cell Biol. 73:59-66(1995).
//
RX   PubMed=9310181; DOI=10.1016/S0300-9084(97)80026-0;
RA   Tzanakakis G.N., Hjerpe A., Karamanos N.K.;
RT   "Proteoglycan synthesis induced by transforming and basic fibroblast
RT   growth factors in human malignant mesothelioma is mediated through
RT   specific receptors and the tyrosine kinase intracellular pathway.";
RL   Biochimie 79:323-332(1997).
//
RX   PubMed=23840376; DOI=10.1371/journal.pone.0065903; PMCID=PMC3688685;
RA   Szulkin A., Nilsonne G., Mundt F., Wasik A.M., Souri P., Hjerpe A.,
RA   Dobra K.;
RT   "Variation in drug sensitivity of malignant mesothelioma cell lines
RT   with substantial effects of selenite and bortezomib, highlights need
RT   for individualized therapy.";
RL   PLoS ONE 8:e65903.1-e65903.14(2013).
//
RX   PubMed=33567673; DOI=10.3390/cancers13040685; PMCID=PMC7915464;
RA   Keller M., Reis K., Hjerpe A., Dobra K., Aspenstrom P.;
RT   "Cytoskeletal organization correlates to motility and invasiveness of
RT   malignant mesothelioma cells.";
RL   Cancers (Basel) 13:685.1-685.20(2021).
//