ID   UM-SCC-81A
AC   CVCL_7783
SY   UMSCC-81A; UMSCC81A; University of Michigan-Squamous Cell Carcinoma-81A
DR   cancercelllines; CVCL_7783
DR   GEO; GSM3631284
DR   IARC_TP53; 21109
DR   Progenetix; CVCL_7783
DR   Wikidata; Q54990923
RX   PubMed=9041179;
RX   PubMed=12884349;
RX   PubMed=15287027;
RX   PubMed=16785414;
RX   PubMed=17312569;
RX   PubMed=19760794;
RX   PubMed=28196595;
RX   PubMed=31090975;
WW   Info; MCLP; -; https://tcpaportal.org/mclp/
CC   Part of: MD Anderson Cell Lines Project.
CC   Sequence variation: Mutation; HGNC; HGNC:11998; TP53; None_reported; -; Zygosity=- (PubMed=12884349).
CC   Omics: Genomics; Whole exome sequencing.
CC   Omics: Proteomics; Expression; Reverse-phase protein array.
CC   Omics: Transcriptomics; RNAseq.
CC   Omics: Variations; CNV analysis.
CC   Derived from site: In situ; Larynx; UBERON=UBERON_0001737.
ST   Source(s): PubMed=19760794
ST   Amelogenin: X
ST   D13S317: 9
ST   D18S51: 14,19
ST   D21S11: 33.2
ST   D3S1358: 15,17
ST   D5S818: 11,12
ST   D7S820: 9,11
ST   D8S1179: 10
ST   FGA: 22
ST   vWA: 17
DI   NCIt; C4044; Laryngeal squamous cell carcinoma
DI   ORDO; Orphanet_494550; Squamous cell carcinoma of the larynx
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
OI   CVCL_7784 ! UM-SCC-81B
SX   Male
AG   53Y
CA   Cancer cell line
DT   Created: 04-04-12; Last updated: 10-04-25; Version: 22
//
RX   PubMed=9041179;
RA   Frank C.J., McClatchey K.D., Devaney K.O., Carey T.E.;
RT   "Evidence that loss of chromosome 18q is associated with tumor
RT   progression.";
RL   Cancer Res. 57:824-827(1997).
//
RX   PubMed=12884349; DOI=10.1002/hed.10274;
RA   Bradford C.R., Zhu S.-B., Ogawa H., Ogawa T., Ubell M., Narayan A.,
RA   Johnson G., Wolf G.T., Fisher S.G., Carey T.E.;
RT   "p53 mutation correlates with cisplatin sensitivity in head and neck
RT   squamous cell carcinoma lines.";
RL   Head Neck 25:654-661(2003).
//
RX   PubMed=15287027; DOI=10.1002/gcc.20066;
RA   Takebayashi S., Hickson A., Ogawa T., Jung K.-Y., Mineta H., Ueda Y.,
RA   Grenman R., Fisher S.G., Carey T.E.;
RT   "Loss of chromosome arm 18q with tumor progression in head and neck
RT   squamous cancer.";
RL   Genes Chromosomes Cancer 41:145-154(2004).
//
RX   PubMed=16785414; DOI=10.1001/archotol.132.6.668;
RA   Worsham M.J., Chen K.M., Meduri V., Nygren A.O.H., Errami A.,
RA   Schouten J.P., Benninger M.S.;
RT   "Epigenetic events of disease progression in head and neck squamous
RT   cell carcinoma.";
RL   Arch. Otolaryngol. Head Neck Surg. 132:668-677(2006).
//
RX   PubMed=17312569; DOI=10.1002/hed.20478;
RA   Lin C.J., Grandis J.R., Carey T.E., Gollin S.M., Whiteside T.L.,
RA   Koch W.M., Ferris R.L., Lai S.Y.;
RT   "Head and neck squamous cell carcinoma cell lines: established models
RT   and rationale for selection.";
RL   Head Neck 29:163-188(2007).
//
RX   PubMed=19760794; DOI=10.1002/hed.21198; PMCID=PMC3292176;
RA   Brenner J.C., Graham M.P., Kumar B., Saunders L.M., Kupfer R.,
RA   Lyons R.H., Bradford C.R., Carey T.E.;
RT   "Genotyping of 73 UM-SCC head and neck squamous cell carcinoma cell
RT   lines.";
RL   Head Neck 32:417-426(2010).
//
RX   PubMed=28196595; DOI=10.1016/j.ccell.2017.01.005; PMCID=PMC5501076;
RA   Li J., Zhao W., Akbani R., Liu W.-B., Ju Z.-L., Ling S.-Y., Vellano C.P.,
RA   Roebuck P., Yu Q.-H., Eterovic A.K., Byers L.A., Davies M.A., Deng W.-L.,
RA   Gopal Y.N.V., Chen G., von Euw E.M., Slamon D.J., Conklin D.,
RA   Heymach J.V., Gazdar A.F., Minna J.D., Myers J.N., Lu Y.-L., Mills G.B.,
RA   Liang H.;
RT   "Characterization of human cancer cell lines by reverse-phase protein
RT   arrays.";
RL   Cancer Cell 31:225-239(2017).
//
RX   PubMed=31090975; DOI=10.1002/hed.25803; PMCID=PMC6692232;
RA   Mann J.E., Kulkarni A., Birkeland A.C., Kafelghazal J., Eisenberg J.,
RA   Jewell B.M., Ludwig M.L., Spector M.E., Jiang H., Carey T.E.,
RA   Brenner J.C.;
RT   "The molecular landscape of the University of Michigan laryngeal
RT   squamous cell carcinoma cell line panel.";
RL   Head Neck 41:3114-3124(2019).
//