ID   UM-SCC-74A
AC   CVCL_7779
SY   UMSCC-74A; UMSCC74A; University of Michigan-Squamous Cell Carcinoma-74A
DR   IARC_TP53; 21107
DR   Wikidata; Q54990912
RX   PubMed=12884349;
RX   PubMed=15287027;
RX   PubMed=17312569;
RX   PubMed=19760794;
RX   PubMed=28196595;
WW   https://tcpaportal.org/mclp/
CC   Part of: MD Anderson Cell Lines Project.
CC   Sequence variation: Mutation; HGNC; 11998; TP53; None_reported; -; Zygosity=- (PubMed=12884349).
CC   Omics: Protein expression by reverse-phase protein arrays.
ST   Source(s): PubMed=19760794
ST   Amelogenin: X
ST   D13S317: 12
ST   D18S51: 17
ST   D21S11: 30,34.2
ST   D3S1358: 15,16
ST   D5S818: 12
ST   D7S820: 11
ST   D8S1179: 12,13
ST   FGA: 21,26
ST   vWA: 15,16
DI   NCIt; C4648; Tongue squamous cell carcinoma
DI   ORDO; Orphanet_457252; Squamous cell carcinoma of the oral tongue
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
OI   CVCL_7780 ! UM-SCC-74B
SX   Male
AG   51Y
CA   Cancer cell line
DT   Created: 04-04-12; Last updated: 21-03-23; Version: 17
//
RX   PubMed=12884349; DOI=10.1002/hed.10274;
RA   Bradford C.R., Zhu S.-B., Ogawa H., Ogawa T., Ubell M., Narayan A.,
RA   Johnson G., Wolf G.T., Fisher S.G., Carey T.E.;
RT   "P53 mutation correlates with cisplatin sensitivity in head and neck
RT   squamous cell carcinoma lines.";
RL   Head Neck 25:654-661(2003).
//
RX   PubMed=15287027; DOI=10.1002/gcc.20066;
RA   Takebayashi S., Hickson A., Ogawa T., Jung K.-Y., Mineta H., Ueda Y.,
RA   Grenman R., Fisher S.G., Carey T.E.;
RT   "Loss of chromosome arm 18q with tumor progression in head and neck
RT   squamous cancer.";
RL   Genes Chromosomes Cancer 41:145-154(2004).
//
RX   PubMed=17312569; DOI=10.1002/hed.20478;
RA   Lin C.J., Grandis J.R., Carey T.E., Gollin S.M., Whiteside T.L.,
RA   Koch W.M., Ferris R.L., Lai S.Y.;
RT   "Head and neck squamous cell carcinoma cell lines: established models
RT   and rationale for selection.";
RL   Head Neck 29:163-188(2007).
//
RX   PubMed=19760794; DOI=10.1002/hed.21198;
RA   Brenner J.C., Graham M.P., Kumar B., Saunders L.M., Kupfer R.,
RA   Lyons R.H., Bradford C.R., Carey T.E.;
RT   "Genotyping of 73 UM-SCC head and neck squamous cell carcinoma cell
RT   lines.";
RL   Head Neck 32:417-426(2010).
//
RX   PubMed=28196595; DOI=10.1016/j.ccell.2017.01.005;
RA   Li J., Zhao W., Akbani R., Liu W.-B., Ju Z.-L., Ling S.-Y., Vellano C.P.,
RA   Roebuck P., Yu Q.-H., Eterovic A.K., Byers L.A., Davies M.A., Deng W.-L.,
RA   Gopal Y.N.V., Chen G., von Euw E.M., Slamon D.J., Conklin D.,
RA   Heymach J.V., Gazdar A.F., Minna J.D., Myers J.N., Lu Y.-L., Mills G.B.,
RA   Liang H.;
RT   "Characterization of human cancer cell lines by reverse-phase protein
RT   arrays.";
RL   Cancer Cell 31:225-239(2017).
//