ID   IT-45R1
AC   CVCL_7677
SY   IT-45 R1; IT45-R1
DR   BCRJ; 0282
DR   JCRB; IFO50076
DR   Wikidata; Q54898354
RX   DOI=10.2220/biomedres.2.11;
RX   PubMed=6602403;
RX   PubMed=6977896;
CC   Doubling time: 60 hours (DOI=10.2220/biomedres.2.11).
CC   Derived from site: In situ; Thymus; UBERON=UBERON_0002370.
CC   Cell type: Epithelial cell of thymus; CL=CL_0002293.
CC   Breed/subspecies: Wistar; RS=RS_0000955.
OX   NCBI_TaxID=10116; ! Rattus norvegicus (Rat)
OI   CVCL_7678 ! IT-45R91
OI   CVCL_E2VH ! IT-45R92
SX   Sex unspecified
AG   5W
CA   Spontaneously immortalized cell line
DT   Created: 04-04-12; Last updated: 10-04-25; Version: 13
//
RX   DOI=10.2220/biomedres.2.11;
RA   Itoh, Tsunetoshi
RA   Aizu, Seiei
RA   Kasahara, Shigeru
RA   Mori, Tom
RT   "Establishment of a functioning epithelial cell line from the rat
RT   thymus. A cell line that induces the differentiation of rat bone
RT   marrow cells into T cell lineage.";
RL   Biomed. Res. 2:11-19(1981).
//
RX   PubMed=6602403;
RA   Kasahara, Shigeru
RA   Itoh, Tsunetoshi
RA   Mori, Tom
RT   "The effect of the supernatant of the thymic epithelial cell line,
RT   IT-45R1 (STEL), on thymocyte reactivity to mitogens.";
RL   Thymus 5:115-119(1983).
//
RX   PubMed=6977896;
RA   Itoh, Tsunetoshi
RA   Kasahara, Shigeru
RA   Mori, Tom
RT   "A thymic epithelial cell line, IT-45R1, induces the differentiation
RT   of prethymic progenitor cells into postthymic cells through direct
RT   contact.";
RL   Thymus 4:69-75(1982).
//