ID   GM03440
AC   CVCL_7388
SY   GM3440; GM-3440; GM 3440; GM03440B
DR   BTO; BTO_0005961
DR   CLO; CLO_0017047
DR   BioSample; SAMN00808407
DR   Coriell; GM03440
DR   GEO; GSM1184262
DR   GEO; GSM1184263
DR   GEO; GSM2064581
DR   GEO; GSM3124649
DR   Wikidata; Q54838068
RX   CelloPub=CLPUB00387;
RX   CelloPub=CLPUB00447;
RX   CelloPub=CLPUB00720;
RX   PubMed=7104995;
RX   PubMed=8316623;
RX   PubMed=12665480;
RX   PubMed=17668376;
RX   PubMed=21490598;
RX   PubMed=24749076;
RX   PubMed=27543334;
RX   PubMed=28444186;
RX   PubMed=30567591;
CC   Population: Caucasian.
CC   Omics: Transcriptomics; Microarray.
CC   Omics: Transcriptomics; RNAseq.
CC   Derived from site: In situ; Leg, skin; UBERON=UBERON_0001511.
CC   Cell type: Fibroblast of skin; CL=CL_0002620.
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Male
AG   20Y
CA   Finite cell line
DT   Created: 04-04-12; Last updated: 10-04-25; Version: 21
//
RX   CelloPub=CLPUB00387;
RA   Coriell L.L., Greene A.E., Mulivor R.A.;
RT   "The human genetic mutant cell repository: list of genetic variants,
RT   chromosomal aberrations and normal cell cultures submitted to the
RT   repository. 7th edition. October 1980.";
RL   (In misc. document) Institute for Medical Research (Camden, N.J.) NIH 80-2011; pp.1-254; National Institutes of Health; Bethesda; USA (1980).
//
RX   CelloPub=CLPUB00447;
RA   Mulivor R.A., Suchy S.F.;
RT   "1992/1993 catalog of cell lines. NIGMS human genetic mutant cell
RT   repository. 16th edition. October 1992.";
RL   (In misc. document) Institute for Medical Research (Camden, N.J.) NIH 92-2011; pp.1-918; National Institutes of Health; Bethesda; USA (1992).
//
RX   CelloPub=CLPUB00720;
RA   Greene A.E., Mulivor R.A.;
RT   "1986/1987 catalog of cell lines. NIGMS human genetic mutant cell
RT   repository. 13th edition. October 1986.";
RL   (In misc. document) Institute for Medical Research (Camden, N.J.) NIH 87-2011; pp.1-549; National Institutes of Health; Bethesda; USA (1986).
//
RX   PubMed=7104995;
RA   Kinsella T.J., Mitchell J.B., McPherson S., Russo A., Tietze F.;
RT   "In vitro X-ray sensitivity in ataxia telangiectasis homozygote and
RT   heterozygote skin fibroblasts under oxic and hypoxic conditions.";
RL   Cancer Res. 42:3950-3956(1982).
//
RX   PubMed=8316623; DOI=10.2307/3578190;
RA   Evans H.H., Ricanati M., Horng M.-F., Jiang Q.-Y., Mencl J.,
RA   Olive P.L.;
RT   "DNA double-strand break rejoining deficiency in TK6 and other human
RT   B-lymphoblast cell lines.";
RL   Radiat. Res. 134:307-315(1993).
//
RX   PubMed=12665480; DOI=10.1096/fj.02-0851com;
RA   Tuo J.-S., Jaruga P., Rodriguez H., Bohr V.A., Dizdaroglu M.;
RT   "Primary fibroblasts of Cockayne syndrome patients are defective in
RT   cellular repair of 8-hydroxyguanine and 8-hydroxyadenine resulting
RT   from oxidative stress.";
RL   FASEB J. 17:668-674(2003).
//
RX   PubMed=17668376; DOI=10.1086/519248; PMCID=PMC1950802;
RA   Prandini P., Deutsch S., Lyle R., Gagnebin M., Delucinge-Vivier C.,
RA   Delorenzi M., Gehrig C., Descombes P., Sherman S.L.,
RA   Dagna-Bricarelli F., Baldo C., Novelli A., Dallapiccola B.,
RA   Antonarakis S.E.;
RT   "Natural gene-expression variation in Down syndrome modulates the
RT   outcome of gene-dosage imbalance.";
RL   Am. J. Hum. Genet. 81:252-263(2007).
//
RX   PubMed=21490598; DOI=10.1038/nature09915; PMCID=PMC3392969;
RA   Brennand K.J., Simone A., Jou J., Gelboin-Burkhart C., Tran N.,
RA   Sangar S., Li Y., Mu Y.-L., Chen G., Yu D.X., McCarthy S.E., Sebat J.,
RA   Gage F.H.;
RT   "Modelling schizophrenia using human induced pluripotent stem cells.";
RL   Nature 473:221-225(2011).
//
RX   PubMed=24749076; DOI=10.1016/j.stemcr.2014.02.006; PMCID=PMC3986587;
RA   Cheung H.-H., Liu X.-Z., Canterel-Thouennon L., Li L., Edmonson C.,
RA   Rennert O.M.;
RT   "Telomerase protects Werner syndrome lineage-specific stem cells from
RT   premature aging.";
RL   Stem Cell Reports 2:534-546(2014).
//
RX   PubMed=27543334; DOI=10.1073/pnas.1610020113; PMCID=PMC5018765;
RA   Reid-Bayliss K.S., Arron S.T., Loeb L.A., Bezrookove V., Cleaver J.E.;
RT   "Why Cockayne syndrome patients do not get cancer despite their DNA
RT   repair deficiency.";
RL   Proc. Natl. Acad. Sci. U.S.A. 113:10151-10156(2016).
//
RX   PubMed=28444186; DOI=10.1093/hmg/ddx141; PMCID=PMC6251520;
RA   Jasoliya M.J., McMackin M.Z., Henderson C.K., Perlman S.L.,
RA   Cortopassi G.A.;
RT   "Frataxin deficiency impairs mitochondrial biogenesis in cells, mice
RT   and humans.";
RL   Hum. Mol. Genet. 26:2627-2633(2017).
//
RX   PubMed=30567591; DOI=10.1186/s13059-018-1599-6; PMCID=PMC6300908;
RA   Fleischer J.G., Schulte R., Tsai H.H., Tyagi S., Ibarra A.,
RA   Shokhirev M.N., Huang L., Hetzer M.W., Navlakha S.;
RT   "Predicting age from the transcriptome of human dermal fibroblasts.";
RL   Genome Biol. 19:221.1-221.8(2018).
//