ID   GM00969
AC   CVCL_7311
SY   GM0969; GM-969; GM 969; GM00969A; GM 969A; GM0969B; GM00969C; GM00969F; C4
DR   CLO; CLO_0029504
DR   Coriell; GM00969
DR   GEO; GSM1316971
DR   GEO; GSM1317008
DR   GEO; GSM3124626
DR   Wikidata; Q54836570
RX   CelloPub=CLPUB00387;
RX   CelloPub=CLPUB00447;
RX   CelloPub=CLPUB00600;
RX   CelloPub=CLPUB00720;
RX   DOI=10.5962/bhl.title.4090;
RX   PubMed=2837086;
RX   PubMed=3745952;
RX   PubMed=6458814;
RX   PubMed=6726265;
RX   PubMed=7380831;
RX   PubMed=12665480;
RX   PubMed=17668376;
RX   PubMed=19896956;
RX   PubMed=26831110;
RX   PubMed=30567591;
CC   Population: Caucasian.
CC   Omics: Transcriptomics; Microarray.
CC   Omics: Transcriptomics; miRNA profiling; Microarray.
CC   Omics: Transcriptomics; RNAseq.
CC   Derived from site: In situ; Skin; UBERON=UBERON_0002097.
CC   Cell type: Fibroblast of skin; CL=CL_0002620.
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Female
AG   2Y
CA   Finite cell line
DT   Created: 04-04-12; Last updated: 10-04-25; Version: 24
CH   CVCL_C9IZ ! CBRCULi011-A
CH   CVCL_DR05 ! CHOPWT1.1
CH   CVCL_DR06 ! CHOPWT1.2
CH   CVCL_DR07 ! CHOPWT1.3
//
RX   PubMed=7380831; DOI=10.1016/S0021-9258(19)70683-8;
RA   Daddona, Peter E.
RA   Frohman, Michael A.
RA   Kelley, William Nimmons
RT   "Human adenosine deaminase and its binding protein in normal and
RT   adenosine deaminase-deficient fibroblast cell strains.";
RL   J. Biol. Chem. 255:5681-5687(1980).
//
RX   PubMed=6458814; DOI=10.1073/pnas.78.10.6451; PMCID=PMC349057;
RA   Scudiero, Dominic A.
RA   Meyer, Sharon A.
RA   Clatterbuck, Brian E.
RA   Tarone, Robert E.
RA   Robbins, Jay H.
RT   "Hypersensitivity to N-methyl-N'-nitro-N-nitrosoguanidine in
RT   fibroblasts from patients with Huntington disease, familial
RT   dysautonomia, and other primary neuronal degenerations.";
RL   Proc. Natl. Acad. Sci. U.S.A. 78:6451-6455(1981).
//
RX   PubMed=30567591; DOI=10.1186/s13059-018-1599-6; PMCID=PMC6300908;
RA   Fleischer, Jason G.
RA   Schulte, Roberta
RA   Tsai, Hsiao H.
RA   Tyagi, Swati
RA   Ibarra, Arkaitz
RA   Shokhirev, Maxim N.
RA   Huang, Ling
RA   Hetzer, Martin W.
RA   Navlakha, Saket
RT   "Predicting age from the transcriptome of human dermal fibroblasts.";
RL   Genome Biol. 19:221.1-221.8(2018).
//
RX   DOI=10.5962/bhl.title.4090;
RA   Coriell, Lewis Lemon
RA   Greene, Arthur E.
RT   "The human genetic mutant cell repository: list of genetic variants,
RT   chromosomal aberrations and normal cell cultures submitted to the
RT   repository. 4th edition. October 1977.";
RL   (In misc. document) Institute for Medical Research (Camden, N.J.); pp.1-171; National Institutes of Health; Bethesda; USA (1977).
//
RX   PubMed=12665480; DOI=10.1096/fj.02-0851com;
RA   Tuo, Jing-Sheng
RA   Jaruga, Pawel
RA   Rodriguez, Henry
RA   Bohr, Vilhelm A.
RA   Dizdaroglu, Miral
RT   "Primary fibroblasts of Cockayne syndrome patients are defective in
RT   cellular repair of 8-hydroxyguanine and 8-hydroxyadenine resulting
RT   from oxidative stress.";
RL   FASEB J. 17:668-674(2003).
//
RX   CelloPub=CLPUB00600;
RA   Coriell, Lewis Lemon
RA   Greene, Arthur E.
RA   Mulivor, Richard A.
RT   "The human genetic mutant cell repository: list of genetic variants,
RT   chromosomal aberrations and normal cell cultures submitted to the
RT   repository. 6th edition. October 1979.";
RL   (In misc. document) Institute for Medical Research (Camden, N.J.) NIH 80-2011; pp.1-168; National Institutes of Health; Bethesda; USA (1979).
//
RX   PubMed=19896956; DOI=10.1016/j.mrfmmm.2009.10.013;
RA   Wilson, Paul F.
RA   Nham, Peter B.
RA   Urbin, Salustra S.
RA   Hinz, John M.
RA   Jones, Irene M.
RA   Thompson, Lawrence H.
RT   "Inter-individual variation in DNA double-strand break repair in human
RT   fibroblasts before and after exposure to low doses of ionizing
RT   radiation.";
RL   Mutat. Res. 683:91-97(2010).
//
RX   CelloPub=CLPUB00447;
RA   Mulivor, Richard A.
RA   Suchy, Sharon F.
RT   "1992/1993 catalog of cell lines. NIGMS human genetic mutant cell
RT   repository. 16th edition. October 1992.";
RL   (In misc. document) Institute for Medical Research (Camden, N.J.) NIH 92-2011; pp.1-918; National Institutes of Health; Bethesda; USA (1992).
//
RX   PubMed=6726265; DOI=10.1136/jnnp.47.4.391; PMCID=PMC1027781;
RA   Robbins, Jay H.
RA   Scudiero, Dominic A.
RA   Otsuka, Fujio
RA   Tarone, Robert E.
RA   Brumback, Roger Alan
RA   Wirtschafter, Jonathan D.
RA   Polinsky, Ronald J.
RA   Barrett, Susanna F.
RA   Moshell, Alan N.
RA   Scarpinato, Ronald G.
RA   Ganges, Mary Bruce
RA   Nee, Linda E.
RA   Meyer, Sharon A.
RA   Clatterbuck, Brian E.
RT   "Hypersensitivity to DNA-damaging agents in cultured cells from
RT   patients with Usher's syndrome and Duchenne muscular dystrophy.";
RL   J. Neurol. Neurosurg. Psychiatry 47:391-398(1984).
//
RX   PubMed=2837086; PMCID=PMC1715274;
RA   Winkler, Janet K.
RA   Suttle, D. Parker
RT   "Analysis of UMP synthase gene and mRNA structure in hereditary orotic
RT   aciduria fibroblasts.";
RL   Am. J. Hum. Genet. 43:86-94(1988).
//
RX   CelloPub=CLPUB00387;
RA   Coriell, Lewis Lemon
RA   Greene, Arthur E.
RA   Mulivor, Richard A.
RT   "The human genetic mutant cell repository: list of genetic variants,
RT   chromosomal aberrations and normal cell cultures submitted to the
RT   repository. 7th edition. October 1980.";
RL   (In misc. document) Institute for Medical Research (Camden, N.J.) NIH 80-2011; pp.1-254; National Institutes of Health; Bethesda; USA (1980).
//
RX   PubMed=26831110; DOI=10.1073/pnas.1525665113; PMCID=PMC4763759;
RA   Iovino, Salvatore
RA   Burkart, Alison M.
RA   Warren, Laura
RA   Patti, Mary-Elizabeth
RA   Kahn, Carl Ronald
RT   "Myotubes derived from human-induced pluripotent stem cells mirror in
RT   vivo insulin resistance.";
RL   Proc. Natl. Acad. Sci. U.S.A. 113:1889-1894(2016).
//
RX   CelloPub=CLPUB00720;
RA   Greene, Arthur E.
RA   Mulivor, Richard A.
RT   "1986/1987 catalog of cell lines. NIGMS human genetic mutant cell
RT   repository. 13th edition. October 1986.";
RL   (In misc. document) Institute for Medical Research (Camden, N.J.) NIH 87-2011; pp.1-549; National Institutes of Health; Bethesda; USA (1986).
//
RX   PubMed=3745952; DOI=10.1111/1523-1747.ep12285424;
RA   Sephel, Gregory Charles
RA   Davidson, Jeffrey M.
RT   "Elastin production in human skin fibroblast cultures and its decline
RT   with age.";
RL   J. Invest. Dermatol. 86:279-285(1986).
//
RX   PubMed=17668376; DOI=10.1086/519248; PMCID=PMC1950802;
RA   Prandini, Paola
RA   Deutsch, Samuel
RA   Lyle, Robert
RA   Gagnebin, Maryline
RA   Delucinge-Vivier, Celine
RA   Delorenzi, Mauro
RA   Gehrig, Corinne
RA   Descombes, Patrick
RA   Sherman, Stephanie L.
RA   Dagna-Bricarelli, Franca
RA   Baldo, Chiara
RA   Novelli, Antonio
RA   Dallapiccola, Bruno
RA   Antonarakis, Stylianos E.
RT   "Natural gene-expression variation in Down syndrome modulates the
RT   outcome of gene-dosage imbalance.";
RL   Am. J. Hum. Genet. 81:252-263(2007).
//