AC   CVCL_7262
SY   Epiteliali Umane Embrionali
DR   BTO; BTO:0000430
DR   BioSample; SAMN03151693
DR   Wikidata; Q54832878
RX   DOI=10.1038/196600a0;
RX   PubMed=2654098;
RX   PubMed=6451928;
RX   PubMed=9691432;
RX   PubMed=13580596;
RX   PubMed=20143388;
CC   Problematic cell line: Contaminated. Shown to be a HeLa derivative (PubMed=6451928; PubMed=20143388). Originally thought to originate from the skin and muscle explant of an embryo.
CC   Registration: International Cell Line Authentication Committee, Register of Misidentified Cell Lines; ICLAC-00044.
CC   Population: African American.
CC   Transformant: NCBI_TaxID; 333761; Human papillomavirus type 18 (HPV18).
CC   Derived from site: In situ; Uterus, cervix; UBERON=UBERON_0000002.
DI   NCIt; C27677; Human papillomavirus-related cervical adenocarcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_0030 ! HeLa
SX   Female
AG   30Y6M
CA   Cancer cell line
DT   Created: 04-04-12; Last updated: 05-10-23; Version: 22
RX   DOI=10.1038/196600a0;
RA   Maio J.J., De Carli L.L.;
RT   "Distribution of alkaline phosphatase variants in a heteroploid strain
RT   of human cells in tissue culture.";
RL   Nature 196:600-601(1962).
RX   PubMed=2654098; DOI=10.1007/BF01005983;
RA   Bolognani Fantin A.M., Menghi G., Franchini A., Bondi A.M., Accili D.,
RA   Fuhrman Conti A.M.;
RT   "Characterization of glycoconjugates in an embryonic human epithelial
RT   line and changes consequent to adaptation to a hyperosmotic medium.";
RL   Histochem. J. 21:79-88(1989).
RX   PubMed=6451928; DOI=10.1126/science.6451928;
RA   Nelson-Rees W.A., Daniels D.W., Flandermeyer R.R.;
RT   "Cross-contamination of cells in culture.";
RL   Science 212:446-452(1981).
RX   PubMed=9691432; DOI=10.1016/s0248-4900(98)80336-5;
RA   Bolognani Fantin A.M., Franchini A., Malgara R., Rebecchi B.,
RA   Fuhrman Conti A.M.;
RT   "Glycoconjugate and adhesion molecule changes during the cell cycle in
RT   a human embryonic epithelial cell line.";
RL   Biol. Cell 90:155-159(1998).
RX   PubMed=13580596;
RA   Terni M., Lo Monaco G.B.;
RT   "Continuous culture of cells derived from human embryos.";
RL   Sperimentale 108:177-185(1958).
RX   PubMed=20143388; DOI=10.1002/ijc.25242;
RA   Capes-Davis A., Theodosopoulos G., Atkin I., Drexler H.G., Kohara A.,
RA   MacLeod R.A.F., Masters J.R.W., Nakamura Y., Reid Y.A., Reddel R.R.,
RA   Freshney R.I.;
RT   "Check your cultures! A list of cross-contaminated or misidentified
RT   cell lines.";
RL   Int. J. Cancer 127:1-8(2010).