ID   ACC-LC-94
AC   CVCL_7032
SY   ACC-LC94; TS1; Aichi Cancer Center-Lung Cancer-94
DR   cancercelllines; CVCL_7032
DR   Cosmic; 934453
DR   Cosmic; 1089221
DR   IARC_TP53; 18789
DR   Wikidata; Q54608233
RX   PubMed=7834619;
RX   PubMed=8384671;
RX   PubMed=8385084;
RX   PubMed=11583962;
RX   PubMed=12794755;
CC   Population: Japanese.
CC   Sequence variation: Mutation; HGNC; HGNC:6407; KRAS; Simple; p.Gly12Asp (c.35G>A); ClinVar=VCV000012582; Zygosity=Unspecified (PubMed=12794755).
CC   Sequence variation: Mutation; HGNC; HGNC:11998; TP53; Simple; p.Asp281Gly (c.842A>G); ClinVar=VCV000141141; Zygosity=Unspecified (PubMed=12794755).
CC   Derived from site: Metastatic; Cervical lymph node; UBERON=UBERON_0002429.
DI   NCIt; C3512; Lung adenocarcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
OI   CVCL_7007 ! ACC-LC-174
SX   Sex unspecified
AG   Age unspecified
CA   Cancer cell line
DT   Created: 04-04-12; Last updated: 19-12-24; Version: 17
//
RX   PubMed=7834619;
RA   Washimi O., Nagatake M., Osada H., Ueda R., Koshikawa T., Seki T.,
RA   Takahashi T., Takahashi T.;
RT   "In vivo occurrence of p16 (MTS1) and p15 (MTS2) alterations
RT   preferentially in non-small cell lung cancers.";
RL   Cancer Res. 55:514-517(1995).
//
RX   PubMed=8384671; DOI=10.1093/oxfordjournals.jjco.a039602;
RA   Hida T., Ariyoshi Y., Kuwabara M., Sugiura T., Takahashi T.,
RA   Takahashi T., Hosoda K., Niitsu Y., Ueda R.;
RT   "Glutathione S-transferase pi levels in a panel of lung cancer cell
RT   lines and its relation to chemo-radiosensitivity.";
RL   Jpn. J. Clin. Oncol. 23:14-19(1993).
//
RX   PubMed=8385084; DOI=10.1111/j.1349-7006.1993.tb02851.x; PMCID=PMC5919128;
RA   Suzuki S., Takahashi T., Nakamura S., Koike K., Ariyoshi Y.,
RA   Takahashi T., Ueda R.;
RT   "Alterations of integrin expression in human lung cancer.";
RL   Jpn. J. Cancer Res. 84:168-174(1993).
//
RX   PubMed=11583962; DOI=10.1016/S0002-9440(10)62521-7; PMCID=PMC1850523;
RA   Haruki N., Harano T., Masuda A., Kiyono T., Takahashi T.,
RA   Tatematsu Y., Shimizu S., Mitsudomi T., Konishi H., Osada H.,
RA   Fujii Y., Takahashi T.;
RT   "Persistent increase in chromosome instability in lung cancer:
RT   possible indirect involvement of p53 inactivation.";
RL   Am. J. Pathol. 159:1345-1352(2001).
//
RX   PubMed=12794755; DOI=10.1002/ijc.11184;
RA   Endoh H., Yatabe Y., Shimizu S., Tajima K., Kuwano H., Takahashi T.,
RA   Mitsudomi T.;
RT   "RASSF1A gene inactivation in non-small cell lung cancer and its
RT   clinical implication.";
RL   Int. J. Cancer 106:45-51(2003).
//