ID   BET-3M
AC   CVCL_6F11
SY   Bronchial Epithelium transformed with pRSV-T 3M
DR   Wikidata; Q54796084
RX   CelloPub=CLPUB00712;
RX   PubMed=8220580;
RX   PubMed=9175740;
RX   PubMed=19935656;
CC   Characteristics: Cell line positive for alternative lengthening of telomeres (ALT+) (CelloPub=CLPUB00712; PubMed=19935656).
CC   Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40) [Note=pRSV-T].
CC   Derived from site: In situ; Lung, bronchus, epithelium; UBERON=UBERON_0002031.
CC   Cell type: Epithelial cell of bronchus; CL=CL_0002328.
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
OI   CVCL_6F09 ! BET-3A
OI   CVCL_6F10 ! BET-3B
OI   CVCL_UI61 ! BET-3K
OI   CVCL_UI62 ! BFT-3B
OI   CVCL_UI63 ! BFT-3K
CA   Transformed cell line
DT   Created: 23-02-16; Last updated: 05-10-23; Version: 10
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RX   CelloPub=CLPUB00712;
RA   Henson J.D.;
RT   "The role of alternative lengthening of telomeres in human cancer.";
RL   Thesis PhD (2006), University of Sydney, Australia.
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RX   PubMed=8220580;
RA   De Silva R., Reddel R.R.;
RT   "Similar simian virus 40-induced immortalization frequency of
RT   fibroblasts and epithelial cells from human large airways.";
RL   Cell. Mol. Biol. Res. 39:101-110(1993).
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RX   PubMed=9175740; DOI=10.1093/hmg/6.6.921;
RA   Bryan T.M., Marusic L., Bacchetti S., Namba M., Reddel R.R.;
RT   "The telomere lengthening mechanism in telomerase-negative immortal
RT   human cells does not involve the telomerase RNA subunit.";
RL   Hum. Mol. Genet. 6:921-926(1997).
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RX   PubMed=19935656; DOI=10.1038/nbt.1587;
RA   Henson J.D., Cao Y., Huschtscha L.I., Chang A.C.-M., Au A.Y.M.,
RA   Pickett H.A., Reddel R.R.;
RT   "DNA C-circles are specific and quantifiable markers of
RT   alternative-lengthening-of-telomeres activity.";
RL   Nat. Biotechnol. 27:1181-1185(2009).
//