ID   PC-3 ML
AC   CVCL_6E90
SY   PC3-ML; PC-3 Metastasis in Lumbar vertebrae
DR   BTO; BTO:0006369
DR   cancercelllines; CVCL_6E90
DR   Wikidata; Q54938411
RX   PubMed=1352184;
RX   PubMed=1773917;
RX   PubMed=22275356;
CC   Population: Caucasian.
CC   Sequence variation: Mutation; HGNC; 11998; TP53; Simple; p.Lys139Argfs*31 (c.414delC) (413delC); ClinVar=VCV000133281; Zygosity=Homozygous (from parent cell line).
CC   Derived from site: Metastatic; Bone; UBERON=UBERON_0002481.
DI   NCIt; C4863; Prostate carcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_0035 ! PC-3
SX   Male
AG   62Y
CA   Cancer cell line
DT   Created: 23-02-16; Last updated: 05-10-23; Version: 12
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RX   PubMed=1352184;
RA   Stearns M.E., Wang M.;
RT   "Taxol blocks processes essential for prostate tumor cell (PC-3 ML)
RT   invasion and metastases.";
RL   Cancer Res. 52:3776-3781(1992).
//
RX   PubMed=1773917; DOI=10.1111/j.1432-0436.1991.tb00250.x;
RA   Wang M., Stearns M.E.;
RT   "Isolation and characterization of PC-3 human prostatic tumor sublines
RT   which preferentially metastasize to select organs in S.C.I.D. mice.";
RL   Differentiation 48:115-125(1991).
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RX   PubMed=22275356; DOI=10.1074/jbc.M111.302547;
RA   Lynch T.P., Ferrer C.M., Jackson S.R., Shahriari K.S., Vosseller K.,
RA   Reginato M.J.;
RT   "Critical role of O-linked beta-N-acetylglucosamine transferase in
RT   prostate cancer invasion, angiogenesis, and metastasis.";
RL   J. Biol. Chem. 287:11070-11081(2012).
//