ID   STA-WT-1
AC   CVCL_6D82
SY   STA-WT1; WT; St. Anna Kinderspital-Wilms Tumor-1
DR   Cosmic; 802241
DR   Wikidata; Q54955810
RX   PubMed=9671307;
RX   PubMed=10397258;
RX   PubMed=11782423;
RX   PubMed=16945155;
CC   From: Children's Cancer Research Institute; Vienna; Austria.
CC   Sequence variation: Gene deletion; HGNC; HGNC:11103; SMARCB1; Zygosity=Heterozygous (PubMed=9671307).
CC   Sequence variation: Mutation; HGNC; HGNC:11103; SMARCB1; Simple; p.Gly317Aspfs*3 (c.950delG); Zygosity=Heterozygous (PubMed=9671307; PubMed=16945155).
CC   Derived from site: In situ; Kidney; UBERON=UBERON_0002113.
DI   NCIt; C40407; Kidney Wilms tumor
DI   ORDO; Orphanet_654; Nephroblastoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Male
AG   1Y9M
CA   Cancer cell line
DT   Created: 23-02-16; Last updated: 19-12-24; Version: 10
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RX   PubMed=9671307; DOI=10.1038/28212;
RA   Versteege I., Sevenet N., Lange J., Rousseau-Merck M.-F., Ambros P.F.,
RA   Handgretinger R., Aurias A., Delattre O.;
RT   "Truncating mutations of hSNF5/INI1 in aggressive paediatric cancer.";
RL   Nature 394:203-206(1998).
//
RX   PubMed=10397258;
RA   Rousseau-Merck M.-F., Versteege I., Legrand I., Couturier J.,
RA   Mairal A., Delattre O., Aurias A.;
RT   "hSNF5/INI1 inactivation is mainly associated with homozygous
RT   deletions and mitotic recombinations in rhabdoid tumors.";
RL   Cancer Res. 59:3152-3156(1999).
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RX   PubMed=11782423; DOI=10.1093/emboj/21.1.31; PMCID=PMC125819;
RA   Craig E., Zhang Z.-K., Davies K.P., Kalpana G.V.;
RT   "A masked NES in INI1/hSNF5 mediates hCRM1-dependent nuclear export:
RT   implications for tumorigenesis.";
RL   EMBO J. 21:31-42(2002).
//
RX   PubMed=16945155; DOI=10.1186/1742-4690-3-56; PMCID=PMC1592304;
RA   Sorin M., Yung E., Wu X.-H., Kalpana G.V.;
RT   "HIV-1 replication in cell lines harboring INI1/hSNF5 mutations.";
RL   Retrovirology 3:56.1-56.15(2006).
//