ID   ATL-17-2
AC   CVCL_6D78
SY   ATL-17-2(+)
DR   RCB; RCB3564
DR   Wikidata; Q54751252
RX   PubMed=2972890;
RX   PubMed=32210945;
CC   Population: Japanese.
CC   Characteristics: IL2 dependent.
CC   Transformant: NCBI_TaxID; 11908; Human T-lymphotropic virus 1 (HTLV-1).
CC   Donor information: Established from a patient suffering from adult T-cell leukemia/lymphoma (ATLL).
CC   Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
CC   Cell type: T-cell; CL=CL_0000084.
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
OI   CVCL_A6SQ ! ATL-17C
SX   Male
AG   38Y
CA   Transformed cell line
DT   Created: 23-02-16; Last updated: 29-06-23; Version: 10
//
RX   PubMed=2972890;
RA   Shirono K., Hattori T., Matsuoka M., Matsushita S., Asou N.,
RA   Takatsuki K.;
RT   "Adult T cell leukemia cell lines that originated from primary
RT   leukemic clones also had a defect of expression of CD3-T cell receptor
RT   complex.";
RL   Leukemia 2:728-733(1988).
//
RX   PubMed=32210945; DOI=10.3389/fmicb.2020.00356; PMCID=PMC7067701;
RA   Maeda M., Tanabe-Shibuya J., Miyazato P., Masutani H., Yasunaga J.-i.,
RA   Usami K., Shimizu A., Matsuoka M.;
RT   "IL-2/IL-2 receptor pathway plays a crucial role in the growth and
RT   malignant transformation of HTLV-1-infected T cells to develop adult
RT   T-cell leukemia.";
RL   Front. Microbiol. 11:356.1-356.17(2020).
//