ID   IPEC-J2 MDR1
AC   CVCL_6C41
DR   Wikidata; Q54897970
RX   PubMed=26651362;
WW   http://healthsciences.ku.dk/news/new-2016/copenhagen-researchers-develop-novel-cell-line-for-screening-of-brain-drugs/
CC   Characteristics: Can be used to screen drug compounds for interactions with human efflux pump P-glycoprotein (P-gp).
CC   Transfected with: HGNC; 40; ABCB1.
CC   Transfected with: UniProtKB; P13249; S.alboniger pac (PuroR).
CC   Derived from site: In situ; Small intestine, jejunum; UBERON=UBERON_0002115.
CC   Cell type: Enterocyte; CL=CL_0000584.
OX   NCBI_TaxID=9823; ! Sus scrofa (Pig)
HI   CVCL_2246 ! IPEC-J2
SX   Sex unspecified
AG   <1D
CA   Spontaneously immortalized cell line
DT   Created: 23-02-16; Last updated: 29-06-23; Version: 8
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RX   PubMed=26651362; DOI=10.1021/acs.molpharmaceut.5b00874;
RA   Saaby L., Helms H.C.C., Brodin B.;
RT   "IPEC-J2 MDR1, a novel high-resistance cell line with functional
RT   expression of human P-glycoprotein (ABCB1) for drug screening
RT   studies.";
RL   Mol. Pharm. 13:640-652(2016).
//