ID   PDL-L2
AC   CVCL_6B13
SY   PDL-L 2
DR   Wikidata; Q54946852
RX   PubMed=12356921;
RX   PubMed=17233813;
RX   PubMed=24949082;
CC   Genetic integration: Method=Transgenic mouse; Gene=UniProtKB; P03070; SV40 large T antigen.
CC   Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40) (Note=tsA58).
CC   Omics: Transcriptomics; Microarray.
CC   Derived from site: In situ; Tooth, periodontal ligament; UBERON=UBERON_0008266.
CC   Cell type: Fibroblast of periodontal ligament; CL=CL_2000017.
CC   Breed/subspecies: C57BL/6 SV40-tsA58 transgenic.
OX   NCBI_TaxID=10090; ! Mus musculus (Mouse)
SX   Sex unspecified
AG   5W
CA   Conditionally immortalized cell line
DT   Created: 23-02-16; Last updated: 10-04-25; Version: 11
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RX   PubMed=12356921; DOI=10.1242/jcs.00098;
RA   Saito Y., Yoshizawa T., Takizawa F., Ikegame M., Ishibashi O.,
RA   Okuda K., Hara K., Ishibashi K., Obinata M., Kawashima H.;
RT   "A cell line with characteristics of the periodontal ligament
RT   fibroblasts is negatively regulated for mineralization and
RT   Runx2/Cbfa1/Osf2 activity, part of which can be overcome by bone
RT   morphogenetic protein-2.";
RL   J. Cell Sci. 115:4191-4200(2002).
//
RX   PubMed=17233813; DOI=10.1111/j.1349-7006.2007.00399.x; PMCID=PMC11159456;
RA   Obinata M.;
RT   "The immortalized cell lines with differentiation potentials: their
RT   establishment and possible application.";
RL   Cancer Sci. 98:275-283(2007).
//
RX   PubMed=24949082; DOI=10.1186/1750-2187-9-5; PMCID=PMC4062770;
RA   Ishibashi O., Inui T.;
RT   "Identification of endoglin-dependent BMP-2-induced genes in the
RT   murine periodontal ligament cell line PDL-L2.";
RL   J. Mol. Signal. 9:5.1-5.6(2014).
//