ID   MCE301
AC   CVCL_6B09
SY   MCE 301
DR   Wikidata; Q54904275
RX   PubMed=11235898;
RX   PubMed=11520047;
RX   PubMed=16678170;
RX   PubMed=17233813;
CC   Genetic integration: Method=Transgenic mouse; Gene=UniProtKB; P03070; SV40 large T antigen.
CC   Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40) (Note=tsA58).
CC   Omics: Transcriptomics; Microarray.
CC   Derived from site: In situ; Embryonic colon, distal; UBERON=UBERON_0008971.
CC   Cell type: Epithelial cell of colon; CL=CL_0011108.
CC   Breed/subspecies: C57BL/6 SV40-tsA58 transgenic.
OX   NCBI_TaxID=10090; ! Mus musculus (Mouse)
SX   Sex unspecified
AG   17-18FD
CA   Conditionally immortalized cell line
DT   Created: 23-02-16; Last updated: 10-04-25; Version: 12
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RX   PubMed=11235898; DOI=10.1247/csf.25.297;
RA   Tabuchi Y., Ohta S., Arai Y., Kawahara M., Ishibashi K., Sugiyama N.,
RA   Horiuchi T., Furusawa M., Obinata M., Fuse H., Takeguchi N.,
RA   Asano S.;
RT   "Establishment and characterization of a colonic epithelial cell line
RT   MCE301 from transgenic mice harboring temperature-sensitive simian
RT   virus 40 large T-antigen gene.";
RL   Cell Struct. Funct. 25:297-307(2000).
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RX   PubMed=11520047; DOI=10.1006/bbrc.2001.5247;
RA   Obinata M.;
RT   "Possible applications of conditionally immortalized tissue cell lines
RT   with differentiation functions.";
RL   Biochem. Biophys. Res. Commun. 286:667-672(2001).
//
RX   PubMed=16678170; DOI=10.1016/j.febslet.2006.04.048;
RA   Tabuchi Y., Takasaki I., Doi T., Ishii Y., Sakai H., Kondo T.;
RT   "Genetic networks responsive to sodium butyrate in colonic epithelial
RT   cells.";
RL   FEBS Lett. 580:3035-3041(2006).
//
RX   PubMed=17233813; DOI=10.1111/j.1349-7006.2007.00399.x; PMCID=PMC11159456;
RA   Obinata M.;
RT   "The immortalized cell lines with differentiation potentials: their
RT   establishment and possible application.";
RL   Cancer Sci. 98:275-283(2007).
//