ID   TC6
AC   CVCL_6A95
SY   TC 6; T immortalized chondrocyte-like cell 6
DR   Wikidata; Q54971837
RX   PubMed=8915772;
RX   PubMed=9224657;
RX   PubMed=10502305;
RX   PubMed=11520047;
RX   PubMed=17233813;
CC   Genetic integration: Method=Transgenic mouse; Gene=UniProtKB; P03070; Simian virus 40 (SV40) large T antigen.
CC   Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40) (Note=tsA58).
CC   Derived from site: In situ; Joint articular cartilage; UBERON=UBERON_0010996.
CC   Cell type: Chondrocyte; CL=CL_0000138.
CC   Breed/subspecies: C57BL/6 SV40-tsA58 transgenic.
OX   NCBI_TaxID=10090; ! Mus musculus (Mouse)
SX   Sex unspecified
AG   2M
CA   Conditionally immortalized cell line
DT   Created: 23-02-16; Last updated: 14-08-25; Version: 9
//
RX   PubMed=11520047; DOI=10.1006/bbrc.2001.5247;
RA   Obinata, Masuo
RT   "Possible applications of conditionally immortalized tissue cell lines
RT   with differentiation functions.";
RL   Biochem. Biophys. Res. Commun. 286:667-672(2001).
//
RX   PubMed=8915772; DOI=10.1002/jbmr.5650111108;
RA   Mataga, Nobuko
RA   Tamura, Masato
RA   Yanai, Nobuyuki
RA   Shinomura, Tamayuki
RA   Kimata, Koji
RA   Obinata, Masao
RA   Noda, Masaki
RT   "Establishment of a novel chondrocyte-like cell line derived from
RT   transgenic mice harboring the temperature-sensitive simian virus 40
RT   large T-antigen gene.";
RL   J. Bone Miner. Res. 11:1646-1654(1996).
//
RX   PubMed=9224657; DOI=10.1046/j.1365-2443.1997.1160314.x;
RA   Obinata, Masuo
RT   "Conditionally immortalized cell lines with differentiated functions
RT   established from temperature-sensitive T-antigen transgenic mice.";
RL   Genes Cells 2:235-244(1997).
//
RX   PubMed=10502305; DOI=10.1002/(SICI)1097-4644(19991101)75:2<338::AID-JCB15>3.0.CO;2-9;
RA   Takazawa, Yuji
RA   Nifuji, Akira
RA   Mataga, Nobuko
RA   Yamauchi, Yasuo
RA   Kurosawa, Hisashi
RA   Noda, Masaki
RT   "Articular cartilage cells immortalized by a temperature sensitive
RT   mutant of SV40 large T antigen survive and form cartilage tissue in
RT   articular cartilage environment.";
RL   J. Cell. Biochem. 75:338-345(1999).
//
RX   PubMed=17233813; DOI=10.1111/j.1349-7006.2007.00399.x; PMCID=PMC11159456;
RA   Obinata, Masuo
RT   "The immortalized cell lines with differentiation potentials: their
RT   establishment and possible application.";
RL   Cancer Sci. 98:275-283(2007).
//