ID   TBR-B
AC   CVCL_6A91
SY   TBRB
DR   Wikidata; Q54971768
RX   PubMed=7796878;
RX   PubMed=10996322;
RX   PubMed=11520047;
RX   PubMed=11776976;
RX   PubMed=17233813;
CC   Genetic integration: Method=Transgenic mouse; Gene=UniProtKB; P03070; SV40 large T antigen.
CC   Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40) (Note=tsA58).
CC   Derived from site: In situ; Bone marrow; UBERON=UBERON_0002371.
CC   Cell type: Stromal cell of bone marrow; CL=CL_0010001.
CC   Breed/subspecies: C57BL/6 SV40-tsA58 transgenic.
OX   NCBI_TaxID=10090; ! Mus musculus (Mouse)
SX   Sex unspecified
AG   2M
CA   Conditionally immortalized cell line
DT   Created: 23-02-16; Last updated: 10-09-24; Version: 9
//
RX   PubMed=7796878; DOI=10.1006/excr.1995.1175;
RA   Okuyama R., Yanai N., Obinata M.;
RT   "Differentiation capacity toward mesenchymal cell lineages of bone
RT   marrow stromal cells established from temperature-sensitive SV40
RT   T-antigen gene transgenic mouse.";
RL   Exp. Cell Res. 218:424-429(1995).
//
RX   PubMed=10996322; DOI=10.1016/S0014-5793(00)01995-5;
RA   Arakawa E., Hasegawa K., Yanai N., Obinata M., Matsuda Y.;
RT   "A mouse bone marrow stromal cell line, TBR-B, shows inducible
RT   expression of smooth muscle-specific genes.";
RL   FEBS Lett. 481:193-196(2000).
//
RX   PubMed=11520047; DOI=10.1006/bbrc.2001.5247;
RA   Obinata M.;
RT   "Possible applications of conditionally immortalized tissue cell lines
RT   with differentiation functions.";
RL   Biochem. Biophys. Res. Commun. 286:667-672(2001).
//
RX   PubMed=11776976; DOI=10.1290/1071-2690(2001)037<0698:OMRMCD>2.0.CO;2;
RA   Yanai N., Obinata M.;
RT   "Oncostatin M regulates mesenchymal cell differentiation and enhances
RT   hematopoietic supportive activity of bone marrow stromal cell lines.";
RL   In Vitro Cell. Dev. Biol. Anim. 37:698-704(2001).
//
RX   PubMed=17233813; DOI=10.1111/j.1349-7006.2007.00399.x; PMCID=PMC11159456;
RA   Obinata M.;
RT   "The immortalized cell lines with differentiation potentials: their
RT   establishment and possible application.";
RL   Cancer Sci. 98:275-283(2007).
//