ID   SPC-A1
AC   CVCL_6955
SY   SPC-A-1; SPCA-1; SPCA1
DR   BTO; BTO_0006512
DR   CCTCC; GDC0050
DR   Cosmic; 1515871
DR   Cosmic; 2664119
DR   TOKU-E; 3573
DR   Wikidata; Q54955522
RX   PubMed=22862169;
RX   PubMed=26116706;
WW   Info; ICLAC; -; https://iclac.org/wp-content/uploads/Cross-Contaminations_v13_distribution.xlsx
CC   Problematic cell line: Contaminated. Shown to be a HeLa derivative (CCRID; PubMed=26116706). Originally thought to be a lung adenocarcinoma.
CC   Registration: International Cell Line Authentication Committee, Register of Misidentified Cell Lines; ICLAC-00608.
CC   Population: African American.
CC   Transformant: NCBI_TaxID; 333761; Human papillomavirus type 18 (HPV18).
CC   Miscellaneous: Formerly the CCRID database had 3 entries describing this cell line (3111C0001CCC000387, 3131C0001000700053, 3142C0001000000050). They were one of the sources for the STR profile of this entry.
CC   Derived from site: In situ; Uterus, cervix; UBERON=UBERON_0000002.
ST   Source(s): CCRID; PubMed=26116706
ST   Amelogenin: X
ST   CSF1PO: 9,10
ST   D12S391: 20,25
ST   D13S317: 12,13.3
ST   D16S539: 9,10
ST   D18S51: 16
ST   D19S433: 13,14
ST   D21S11: 27,28
ST   D2S1338: 17
ST   D3S1358: 15,18
ST   D5S818: 11,12
ST   D6S1043: 18,19
ST   D7S820: 8,12
ST   D8S1179: 12
ST   FGA: 21
ST   Penta D: 8,15
ST   Penta E: 7,17
ST   TH01: 7
ST   TPOX: 8,12
ST   vWA: 16,18
DI   NCIt; C27677; Human papillomavirus-related endocervical adenocarcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_0030 ! HeLa
SX   Female
AG   30Y6M
CA   Cancer cell line
DT   Created: 04-04-12; Last updated: 10-04-25; Version: 18
//
RX   PubMed=22862169; DOI=10.4149/neo_2012_087;
RA   Zhou C.-H., Yang S.-F., Li P.-Q.;
RT   "Human lung cancer cell line SPC-A1 contains cells with
RT   characteristics of cancer stem cells.";
RL   Neoplasma 59:685-692(2012).
//
RX   PubMed=26116706; DOI=10.1096/fj.14-266718;
RA   Ye F., Chen C.-G., Qin J., Liu J., Zheng C.-Y.;
RT   "Genetic profiling reveals an alarming rate of cross-contamination
RT   among human cell lines used in China.";
RL   FASEB J. 29:4268-4272(2015).
//