ID   QSG-7701
AC   CVCL_6944
SY   QSG7701
DR   TOKU-E; 4021
DR   Wikidata; Q54948938
RX   CelloPub=CLPUB00100;
RX   PubMed=20564214;
RX   PubMed=26116706;
RX   PubMed=28807831;
WW   Info; ICLAC; -; https://iclac.org/wp-content/uploads/Cross-Contaminations_v13_distribution.xlsx
CC   Problematic cell line: Contaminated. Shown to be a HeLa derivative (PubMed=26116706; PubMed=28807831). Originally thought to originate from an immortalized but non-transformed hepatocytes from a 35 year old female.
CC   Registration: International Cell Line Authentication Committee, Register of Misidentified Cell Lines; ICLAC-00553.
CC   Population: African American.
CC   Transformant: NCBI_TaxID; 333761; Human papillomavirus type 18 (HPV18).
CC   Miscellaneous: Formerly the CCRID database had an entry describing this cell line (3131C0001000200007). It was one of the sources for the STR profile of this entry.
CC   Derived from site: In situ; Uterus, cervix; UBERON=UBERON_0000002.
ST   Source(s): CCRID; PubMed=26116706
ST   Amelogenin: X
ST   CSF1PO: 10
ST   D13S317: 13.3
ST   D16S539: 9,10
ST   D18S51: 16
ST   D19S433: 13
ST   D21S11: 27,28
ST   D2S1338: 17
ST   D3S1358: 15,18
ST   D5S818: 11,12
ST   D7S820: 12
ST   D8S1179: 12
ST   FGA: 18,21
ST   Penta D: 8,15
ST   Penta E: 7,8,17
ST   TH01: 7
ST   TPOX: 12
ST   vWA: 16,18
DI   NCIt; C27677; Human papillomavirus-related endocervical adenocarcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_0030 ! HeLa
SX   Female
AG   30Y6M
CA   Cancer cell line
DT   Created: 04-04-12; Last updated: 10-04-25; Version: 23
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RX   CelloPub=CLPUB00100;
RA   Zhu, De-Hou
RA   Wang, Jin-Bing
RT   "Establishment and comparison of non-malignant liver cell QSG-7701 and
RT   liver cancer cells.";
RL   Zhong Liu Fang Zhi Yan Jiu 5:7-9(1979).
//
RX   PubMed=26116706; DOI=10.1096/fj.14-266718;
RA   Ye, Fang
RA   Chen, Chu-Guang
RA   Qin, Jian
RA   Liu, Jie
RA   Zheng, Cong-Yi
RT   "Genetic profiling reveals an alarming rate of cross-contamination
RT   among human cell lines used in China.";
RL   FASEB J. 29:4268-4272(2015).
//
RX   PubMed=28807831; DOI=10.1016/j.jhep.2017.08.002;
RA   Rebouissou, Sandra
RA   Zucman-Rossi, Jessica
RA   Moreau, Richard
RA   Qiu, Zhi-Xin
RA   Hui, Li-Jian
RT   "Note of caution: contaminations of hepatocellular cell lines.";
RL   J. Hepatol. 67:896-897(2017).
//
RX   PubMed=20564214; DOI=10.1002/jcb.22632;
RA   Zhang, Fang
RA   Xu, Ren
RA   Zhao, Mu-Jun
RT   "QSG-7701 human hepatocytes form polarized acini in three-dimensional
RT   culture.";
RL   J. Cell. Biochem. 110:1175-1186(2010).
//