ID   LTEP-a2
AC   CVCL_6929
SY   LTEP-A2; LTEP a2; LTEP-a-2; LTEPa2
DR   Cosmic; 2664118
DR   Wikidata; Q54903172
RX   PubMed=1889334;
RX   PubMed=2988714;
RX   PubMed=3471311;
RX   PubMed=6872840;
RX   PubMed=26116706;
CC   Problematic cell line: Contaminated. Shown to be a HeLa derivative (PubMed=26116706). Originally thought to originate from a 46 year old female patient with a lung adenocarcinoma.
CC   Registration: International Cell Line Authentication Committee, Register of Misidentified Cell Lines; ICLAC-00576.
CC   Population: African American.
CC   Transformant: NCBI_TaxID; 333761; Human papillomavirus type 18 (HPV18).
CC   Miscellaneous: Formerly the CCRID database had an entry describing this cell line (3131C0001000700033). It was one of the sources for the STR profile of this entry.
CC   Derived from site: In situ; Uterus, cervix; UBERON=UBERON_0000002.
ST   Source(s): CCRID; PubMed=26116706
ST   Amelogenin: X
ST   CSF1PO: 9,10
ST   D12S391: 20,25
ST   D13S317: 12,13.3
ST   D16S539: 9,10
ST   D18S51: 16
ST   D19S433: 13,14
ST   D21S11: 27,28
ST   D2S1338: 17
ST   D3S1358: 15,18
ST   D5S818: 11,12
ST   D6S1043: 18,19
ST   D7S820: 8,12
ST   D8S1179: 12
ST   FGA: 21
ST   Penta D: 8,15
ST   Penta E: 7,17
ST   TH01: 7
ST   TPOX: 8,12
ST   vWA: 16,18
DI   NCIt; C27677; Human papillomavirus-related cervical adenocarcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_0030 ! HeLa
SX   Female
AG   30Y6M
CA   Cancer cell line
DT   Created: 04-04-12; Last updated: 02-05-24; Version: 17
RX   PubMed=1889334;
RA   He B.;
RT   "Invasion of human lung adenocarcinoma cell line LTEP-a2 into various
RT   organs of different species.";
RL   Zhonghua Zhong Liu Za Zhi 13:16-19(1991).
RX   PubMed=2988714;
RA   Wang H., Lai B.-T., Zhan X.-P., Liu G.-Z., He L.-X., Tian G.-Q.,
RA   Huang Z.-Y., Bo Z.-Y., Wu B.-Q., Tang Y.;
RT   "Establishment of five human pulmonary carcinoma cell lines and their
RT   biologic properties.";
RL   Zhonghua Yi Xue Za Zhi 65:208-211(1985).
RX   PubMed=3471311; DOI=10.1016/0165-4608(87)90066-5;
RA   Fan Y.-S., Li P.;
RT   "Cytogenetic studies of four human lung adenocarcinoma cell lines.";
RL   Cancer Genet. Cytogenet. 26:317-325(1987).
RX   PubMed=6872840;
RA   Wang H., Lai B.-T., Zhan Q.-P., He L.-X., Tian G.-Q., Huang Z.-Y.,
RA   Be Z.-Y., Kao J.;
RT   "Establishment of two human pulmonary adenocarcinoma cell lines
RT   (LTEP-a-1, LTEP-a-2) and their biologic properties.";
RL   Zhonghua Zhong Liu Za Zhi 5:85-88(1983).
RX   PubMed=26116706; DOI=10.1096/fj.14-266718;
RA   Ye F., Chen C.-G., Qin J., Liu J., Zheng C.-Y.;
RT   "Genetic profiling reveals an alarming rate of cross-contamination
RT   among human cell lines used in China.";
RL   FASEB J. 29:4268-4272(2015).