ID   HMT-3522
AC   CVCL_6855
SY   HMT3522
DR   BTO; BTO:0003884
DR   Wikidata; Q54889967
RX   DOI=10.1016/B978-0-12-333530-2.50009-5;
RX   PubMed=3558253;
RX   PubMed=7495986;
RX   PubMed=7828152;
RX   PubMed=7982476;
CC   Population: Caucasian.
CC   Characteristics: EGF dependent.
CC   Donor information: Established from a nontumorigenic fibrocystic breast lesion (PubMed=3558253).
CC   Derived from site: In situ; Breast, epithelium; UBERON=UBERON_0008359.
CC   Cell type: Epithelial cell of mammary gland; CL=CL_0002327.
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Female
AG   50Y
CA   Spontaneously immortalized cell line
DT   Created: 04-04-12; Last updated: 02-05-24; Version: 14
RX   DOI=10.1016/B978-0-12-333530-2.50009-5;
RA   Leibovitz A.;
RT   "Cell lines from human breast.";
RL   (In) Atlas of human tumor cell lines; Hay R.J., Park J.-G., Gazdar A.F. (eds.); pp.161-184; Academic Press; New York (1994).
RX   PubMed=3558253; DOI=10.1007/BF02623578;
RA   Briand P., Petersen O.W., van Deurs B.;
RT   "A new diploid nontumorigenic human breast epithelial cell line
RT   isolated and propagated in chemically defined medium.";
RL   In Vitro Cell. Dev. Biol. 23:181-188(1987).
RX   PubMed=7495986; DOI=10.1006/scbi.1995.0021;
RA   Weaver V.M., Howlett A.R., Langton-Webster B.C., Petersen O.W.,
RA   Bissell M.J.;
RT   "The development of a functionally relevant cell culture model of
RT   progressive human breast cancer.";
RL   Semin. Cancer Biol. 6:175-184(1995).
RX   PubMed=7828152; DOI=10.1016/0165-4608(94)90089-2;
RA   Nielsen K.V., Madsen M.W., Briand P.;
RT   "In vitro karyotype evolution and cytogenetic instability in the
RT   non-tumorigenic human breast epithelial cell line HMT-3522.";
RL   Cancer Genet. Cytogenet. 78:189-199(1994).
RX   PubMed=7982476; DOI=10.1006/excr.1994.1355;
RA   Moyret C., Madsen M.W., Cooke J., Briand P., Theillet C.;
RT   "Gradual selection of a cellular clone presenting a mutation at codon
RT   179 of the p53 gene during establishment of the immortalized human
RT   breast epithelial cell line HMT-3522.";
RL   Exp. Cell Res. 215:380-385(1994).