ID   Tca8113
AC   CVCL_6851
SY   TCA8113; Tca-8113
DR   BTO; BTO_0006058
DR   Cosmic; 851222
DR   KCB; KCB 93034YJ
DR   Wikidata; Q54971846
RX   PubMed=3464389;
RX   PubMed=26116706;
RX   PubMed=28851942;
WW   Info; ICLAC; -; https://iclac.org/wp-content/uploads/Cross-Contaminations_v13_distribution.xlsx
CC   Problematic cell line: Contaminated. Shown to be a HeLa derivative (PubMed=26116706; PubMed=28851942). Originally thought to originate from a female patient with a tongue squamous cell carcinoma.
CC   Registration: International Cell Line Authentication Committee, Register of Misidentified Cell Lines; ICLAC-00578.
CC   Population: African American.
CC   Transformant: NCBI_TaxID; 333761; Human papillomavirus type 18 (HPV18).
CC   Miscellaneous: Formerly the CCRID database had 3 entries describing this cell line (3111C0001CCC000296, 3131C0001000700077, 3142C0001000000067). They were one of the sources for the STR profile of this entry.
CC   Derived from site: In situ; Uterus, cervix; UBERON=UBERON_0000002.
ST   Source(s): CCRID; PubMed=26116706; PubMed=28851942
ST   Amelogenin: X
ST   CSF1PO: 9,10
ST   D12S391: 20,25
ST   D13S317: 12,13.3
ST   D16S539: 9,10
ST   D18S51: 16
ST   D19S433: 13,14
ST   D21S11: 27,28
ST   D2S1338: 17
ST   D3S1358: 15,18
ST   D5S818: 11,12
ST   D6S1043: 18,19
ST   D7S820: 8,12
ST   D8S1179: 12,13
ST   FGA: 21
ST   Penta D: 8,15
ST   Penta E: 7,17
ST   TH01: 7
ST   TPOX: 8,12
ST   vWA: 16,18
DI   NCIt; C27677; Human papillomavirus-related endocervical adenocarcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_0030 ! HeLa
SX   Female
AG   30Y6M
CA   Cancer cell line
DT   Created: 04-04-12; Last updated: 10-04-25; Version: 20
CH   CVCL_7906 ! Tca8113-P160
CH   CVCL_7907 ! Tca8113-P60
CH   CVCL_9U53 ! Tca8113/CBP [Chengdu]
CH   CVCL_T058 ! Tca8113/CBP [Chongqing]
CH   CVCL_9U54 ! Tca8113/PYM [Changsha]
CH   CVCL_9U55 ! Tca8113/PYM [Chengdu]
//
RX   PubMed=3464389;
RA   Xu, Xiu-Qi
RA   He, Rong-Gen
RA   Zhou, Xiao-Jian
RA   Zhang, Xiu-Li
RA   Qiu, Wei-Liu
RA   Xu, Liang-Zhong
RA   Liu, Yi-Fa
RT   "Chromosome study on the Tca8113 cell line derived from squamous cell
RT   carcinoma of the human tongue.";
RL   Zhonghua Zhong Liu Za Zhi 8:112-114(1986).
//
RX   PubMed=26116706; DOI=10.1096/fj.14-266718;
RA   Ye, Fang
RA   Chen, Chu-Guang
RA   Qin, Jian
RA   Liu, Jie
RA   Zheng, Cong-Yi
RT   "Genetic profiling reveals an alarming rate of cross-contamination
RT   among human cell lines used in China.";
RL   FASEB J. 29:4268-4272(2015).
//
RX   PubMed=28851942; DOI=10.1038/s41598-017-09660-w; PMCID=PMC5575032;
RA   Bian, Xiao-Cui
RA   Yang, Zhen-Li
RA   Feng, Hai-Liang
RA   Sun, Hao
RA   Liu, Yu-Qin
RT   "A combination of species identification and STR profiling identifies
RT   cross-contaminated cells from 482 human tumor cell lines.";
RL   Sci. Rep. 7:9774.1-9774.10(2017).
//