ID   MM5.1 [Human myeloma]
AC   CVCL_6686
DR   Cosmic; 720766
DR   Wikidata; Q54906154
RX   DOI=10.1007/0-306-46877-8_4;
RX   PubMed=9009094;
RX   PubMed=10936422;
RX   PubMed=11157491;
WW   http://www.cells-talk.com/index.php/page/copelibrary?key=MM5%2e1
CC   Characteristics: Produces IgA kappa.
CC   Characteristics: Requires bone marrow stromal cells for growth.
CC   Derived from site: In situ; Bone marrow; UBERON=UBERON_0002371.
DI   NCIt; C3242; Plasma cell myeloma
DI   ORDO; Orphanet_29073; Multiple myeloma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Male
AG   55Y
CA   Cancer cell line
DT   Created: 04-04-12; Last updated: 29-06-23; Version: 14
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RX   DOI=10.1007/0-306-46877-8_4;
RA   Jernberg-Wiklund H., Nilsson K.;
RT   "Multiple myeloma cell lines.";
RL   (In) Human cell culture. Vol. 3. Cancer cell lines part 3; Masters J.R.W., Palsson B.O. (eds.); pp.81-155; Kluwer Academic Publishers; New York (2000).
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RX   PubMed=9009094; DOI=10.1038/sj.leu.2400564;
RA   Van Riet I., De Greef C., Aharchi F., Woischwill C., De Waele M.,
RA   Bakkus M.H.C., Lacor P., Schots R., Van Camp B.;
RT   "Establishment and characterization of a human stroma-dependent
RT   myeloma cell line (MM5.1) and its stroma-independent variant
RT   (MM5.2).";
RL   Leukemia 11:284-293(1997).
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RX   PubMed=10936422; DOI=10.1016/S0145-2126(99)00195-2;
RA   Drexler H.G., Matsuo Y.;
RT   "Malignant hematopoietic cell lines: in vitro models for the study of
RT   multiple myeloma and plasma cell leukemia.";
RL   Leuk. Res. 24:681-703(2000).
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RX   PubMed=11157491; DOI=10.1182/blood.V97.3.729;
RA   Chesi M., Brents L.A., Ely S.A., Bais C., Robbiani D.F., Mesri E.A.,
RA   Kuehl W.M., Bergsagel P.L.;
RT   "Activated fibroblast growth factor receptor 3 is an oncogene that
RT   contributes to tumor progression in multiple myeloma.";
RL   Blood 97:729-736(2001).
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