ID   MCF-7TN-R
AC   CVCL_6674
DR   cancercelllines; CVCL_6674
DR   Wikidata; Q54904410
RX   PubMed=15138590;
CC   Population: Caucasian.
CC   Sequence variation: Gene deletion; HGNC; HGNC:1787; CDKN2A; Zygosity=Homozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; HGNC:4172; GATA3; Simple; p.Asp336Glyfs*17 (c.1006dupG); Zygosity=Heterozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; HGNC:8975; PIK3CA; Simple; p.Glu545Lys (c.1633G>A); ClinVar=VCV000013655; Zygosity=Heterozygous (from parent cell line).
CC   Derived from site: Metastatic; Pleural effusion; UBERON=UBERON_0000175.
DI   NCIt; C4194; Invasive breast carcinoma of no special type
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_6673 ! MCF-7N
SX   Female
AG   69Y
CA   Cancer cell line
DT   Created: 04-04-12; Last updated: 19-12-24; Version: 20
//
RX   PubMed=15138590; DOI=10.3892/ijo.24.6.1473;
RA   Weldon C.B., Parker A.P., Patten D., Elliott S., Tang Y., Frigo D.E.,
RA   Dugan C.M., Coakley E.L., Butler N.N., Clayton J.L., Alam J.,
RA   Curiel T.J., Beckman B.S., Jaffe B.M., Burow M.E.;
RT   "Sensitization of apoptotically-resistant breast carcinoma cells to
RT   TNF and TRAIL by inhibition of p38 mitogen-activated protein kinase
RT   signaling.";
RL   Int. J. Oncol. 24:1473-1480(2004).
//