ID   PAGRS-28
AC   CVCL_6641
SY   PA-GRS28; Grs-28
DR   Wikidata; Q54937469
RX   PubMed=2171916;
RX   PubMed=2845413;
RX   PubMed=15541573;
CC   Genetic integration: Method=Transfection/transduction; Gene=HGNC; HGNC:5173; HRAS (Note=With p.Gly12Val).
CC   Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40).
CC   Derived from site: In situ; Ovary, ovarian follicle, granulosa cell layer; UBERON=UBERON_0005170.
CC   Cell type: Granulosa cell; CL=CL_0000501.
OX   NCBI_TaxID=10116; ! Rattus norvegicus (Rat)
SX   Female
AG   26D
CA   Transformed cell line
DT   Created: 04-04-12; Last updated: 19-12-24; Version: 14
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RX   PubMed=2845413; DOI=10.1073/pnas.85.20.7582; PMCID=PMC282236;
RA   Amsterdam, Abraham
RA   Zauberman, Arie
RA   Meir, Gila
RA   Pinhasi-Kimhi, Orit
RA   Suh, Byung-Sun
RA   Oren, Moshe
RT   "Cotransfection of granulosa cells with simian virus 40 and Ha-RAS
RT   oncogene generates stable lines capable of induced steroidogenesis.";
RL   Proc. Natl. Acad. Sci. U.S.A. 85:7582-7586(1988).
//
RX   PubMed=2171916; DOI=10.1210/endo-127-5-2489;
RA   Suh, Byung-Sun
RA   Amsterdam, Abraham
RT   "Establishment of highly steroidogenic granulosa cell lines by
RT   cotransfection with SV40 and Ha-ras oncogene: induction of
RT   steroidogenesis by cyclic adenosine 3'-5'-monophosphate and its
RT   suppression by phorbol ester.";
RL   Endocrinology 127:2489-2500(1990).
//
RX   PubMed=15541573; DOI=10.1016/j.mce.2004.04.018;
RA   Havelock, Jon Christopher
RA   Rainey, William E.
RA   Carr, Bruce R.
RT   "Ovarian granulosa cell lines.";
RL   Mol. Cell. Endocrinol. 228:67-78(2004).
//