ID   BEL-7404
AC   CVCL_6568
SY   Bel-7404; BEL 7404; Bel 7404; BEL7404; Bel7404; 7404
DR   BTO; BTO_0005814
DR   ChEMBL-Cells; CHEMBL3307908
DR   ChEMBL-Targets; CHEMBL614280
DR   GEO; GSM743502
DR   GEO; GSM936755
DR   GEO; GSM1374401
DR   PubChem_Cell_line; CVCL_6568
DR   Wikidata; Q54795973
RX   DOI=10.1007/978-4-431-68349-0_4;
RX   PubMed=6154311;
RX   PubMed=6275024;
RX   PubMed=11774261;
RX   PubMed=23505090;
RX   PubMed=28807831;
WW   Info; ICLAC; -; https://iclac.org/wp-content/uploads/Cross-Contaminations_v13_distribution.xlsx
CC   Problematic cell line: Contaminated. Shown to be a HeLa derivative (PubMed=28807831). Originally thought to originate from a 69 year old male patient with a hepatocellular carcinoma.
CC   Registration: International Cell Line Authentication Committee, Register of Misidentified Cell Lines; ICLAC-00550.
CC   Population: African American.
CC   Doubling time: 26 hours (PubMed=6154311).
CC   Transformant: NCBI_TaxID; 333761; Human papillomavirus type 18 (HPV18).
CC   Omics: Transcriptomics; Microarray.
CC   Omics: Variations; SNP array analysis.
CC   Miscellaneous: Formerly the CCRID database had an entry describing this cell line (3131C0001000700064). It was the sole source for the STR profile of this entry.
CC   Derived from site: In situ; Uterus, cervix; UBERON=UBERON_0000002.
ST   Source(s): CCRID
ST   Amelogenin: X
ST   CSF1PO: 9,10
ST   D13S317: 12,13.3
ST   D16S539: 9,10
ST   D18S51: 16
ST   D19S433: 13,14
ST   D21S11: 27,28
ST   D2S1338: 17
ST   D3S1358: 18
ST   D5S818: 11,12
ST   D7S820: 8,12
ST   D8S1179: 12
ST   FGA: 21
ST   TH01: 7
ST   TPOX: 8,12
ST   vWA: 16,18
DI   NCIt; C27677; Human papillomavirus-related endocervical adenocarcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_0030 ! HeLa
SX   Female
AG   30Y6M
CA   Cancer cell line
DT   Created: 04-04-12; Last updated: 10-04-25; Version: 30
CH   CVCL_IP16 ! BEL-7404-CP.3
//
RX   PubMed=28807831; DOI=10.1016/j.jhep.2017.08.002;
RA   Rebouissou, Sandra
RA   Zucman-Rossi, Jessica
RA   Moreau, Richard
RA   Qiu, Zhi-Xin
RA   Hui, Li-Jian
RT   "Note of caution: contaminations of hepatocellular cell lines.";
RL   J. Hepatol. 67:896-897(2017).
//
RX   PubMed=6154311; DOI=10.1360/ya1980-23-2-236;
RA   Chen, Rui-Ming
RA   Zhu, De-Hou
RA   Ye, Xiu-Zhen
RA   Shen, Ding-Wu
RA   Lu, Rong-Hua
RT   "Establishment of three human liver carcinoma cell lines and some of
RT   their biological characteristics in vitro.";
RL   Sci. Sin. 23:236-247(1980).
//
RX   DOI=10.1007/978-4-431-68349-0_4;
RA   Alexander, Jennifer J.
RT   "Human hepatoma cell lines.";
RL   (In book chapter) Neoplasms of the liver; Okuda, Kunio & Ishak, Kamal George (eds.); pp.47-56; Springer; Tokyo; Japan (1987).
//
RX   PubMed=6275024; DOI=10.1099/0022-1317-57-1-95;
RA   Koshy, Rajen
RA   Maupas, Philippe
RA   Muller, R.
RA   Hofschneider, Peter Hans
RT   "Detection of hepatitis B virus-specific DNA in the genomes of human
RT   hepatocellular carcinoma and liver cirrhosis tissues.";
RL   J. Gen. Virol. 57:95-102(1981).
//
RX   PubMed=23505090; DOI=10.1002/hep.26402;
RA   Wang, Kai
RA   Lim, Ho Yeong
RA   Shi, Stephanie
RA   Lee, Jeeyun
RA   Deng, Shi-Bing
RA   Xie, Tao
RA   Zhu, Zhou
RA   Wang, Yu-Li
RA   Pocalyko, David
RA   Yang, Wei Jennifer
RA   Rejto, Paul A.
RA   Mao, Mao
RA   Park, Cheol-Keun
RA   Xu, Jiang-Chun
RT   "Genomic landscape of copy number aberrations enables the
RT   identification of oncogenic drivers in hepatocellular carcinoma.";
RL   Hepatology 58:706-717(2013).
//
RX   PubMed=11774261; DOI=10.1002/ijc.1597;
RA   Zhang, Ru-Gang
RA   Wang, Xing-Wang
RA   Guo, Li-Xia
RA   Xie, Hong
RT   "Growth inhibition of BEL-7404 human hepatoma cells by expression of
RT   mutant telomerase reverse transcriptase.";
RL   Int. J. Cancer 97:173-179(2002).
//