ID   MS1 VEGF
AC   CVCL_6503
DR   CLO; CLO_0007876
DR   ATCC; CRL-2460
DR   BCRC; 60369
DR   JCRB; NIHS0321
DR   Wikidata; Q54906800
RX   PubMed=10751370;
CC   Genetic integration: Method=Transduction; Gene=HGNC; HGNC:12680; VEGFA.
CC   Genetic integration: Method=Transduction; Gene=UniProtKB; P13249; S.alboniger pac (PuroR).
CC   Genetic integration: Method=Transduction; Gene=UniProtKB; P03070; SV40 large T antigen.
CC   Genetic integration: Method=Transduction; Gene=UniProtKB; P00552; Transposon Tn5 neo.
CC   Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40) (Note=tsA58-3).
CC   Discontinued: JCRB; NIHS0321; true.
CC   Derived from site: In situ; Pancreas, islets of Langerhans; UBERON=UBERON_0000006.
CC   Cell type: Endothelial cell; CL=CL_0000115.
CC   Breed/subspecies: C57BL/6.
OX   NCBI_TaxID=10090; ! Mus musculus (Mouse)
HI   CVCL_6502 ! Mile Sven 1
SX   Sex unspecified
AG   Adult
CA   Transformed cell line
DT   Created: 04-04-12; Last updated: 10-04-25; Version: 19
//
RX   PubMed=10751370; DOI=10.1016/S0002-9440(10)65015-8; PMCID=PMC1876889;
RA   Arbiser J.L., Larsson H., Claesson-Welsh L., Bai X.-H.,
RA   LaMontagne K.R. Jr., Weiss S.W., Soker S., Flynn E., Brown L.F.;
RT   "Overexpression of VEGF 121 in immortalized endothelial cells causes
RT   conversion to slowly growing angiosarcoma and high level expression of
RT   the VEGF receptors VEGFR-1 and VEGFR-2 in vivo.";
RL   Am. J. Pathol. 156:1469-1476(2000).
//