ID   SVR
AC   CVCL_6455
SY   SVEN 1 ras
DR   CLO; CLO_0009178
DR   ATCC; CRL-2280
DR   BCRC; 60219
DR   ChEMBL-Cells; CHEMBL3307724
DR   ChEMBL-Targets; CHEMBL614869
DR   JCRB; NIHS0317
DR   PubChem_Cell_line; CVCL_6455
DR   Wikidata; Q54971053
RX   PubMed=9023347;
WW   Info; Thermo Fisher; -; https://www.thermofisher.com/ch/en/home/technical-resources/cell-lines/s/cell-lines-detail-127.html
CC   Genetic integration: Method=Transduction; Gene=UniProtKB; P00557; Escherichia coli hygromycin-B 4-O-kinase (hph) (HygR).
CC   Genetic integration: Method=Transduction; Gene=UniProtKB; P01115; Harvey murine sarcoma virus H-Ras (V-Ha-ras).
CC   Genetic integration: Method=Transduction; Gene=UniProtKB; P03070; SV40 large T antigen.
CC   Genetic integration: Method=Transduction; Gene=UniProtKB; P00552; Transposon Tn5 neo.
CC   Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40) (Note=tsA58-3).
CC   Discontinued: JCRB; NIHS0317; true.
CC   Derived from site: In situ; Pancreas, islets of Langerhans; UBERON=UBERON_0000006.
CC   Cell type: Endothelial cell; CL=CL_0000115.
CC   Breed/subspecies: C57BL/6.
OX   NCBI_TaxID=10090; ! Mus musculus (Mouse)
HI   CVCL_6502 ! Mile Sven 1
SX   Sex unspecified
AG   Adult
CA   Transformed cell line
DT   Created: 04-04-12; Last updated: 10-04-25; Version: 21
//
RX   PubMed=9023347; DOI=10.1073/pnas.94.3.861; PMCID=PMC19604;
RA   Arbiser J.L., Moses M.A., Fernandez C.A., Ghiso N., Cao Y.-H.,
RA   Klauber N., Frank D.A., Brownlee M., Flynn E., Parangi S., Byers H.R.,
RA   Folkman J.;
RT   "Oncogenic H-ras stimulates tumor angiogenesis by two distinct
RT   pathways.";
RL   Proc. Natl. Acad. Sci. U.S.A. 94:861-866(1997).
//