ID   CHO-DXB11 CTLA4 Ig-24
AC   CVCL_6384
SY   CTLA4 Ig-24; CTLA4Ig-24
DR   CLO; CLO_0002634
DR   ATCC; CRL-10762
DR   CCRID; 3101HAMGNHa9
DR   CLS; 305014
DR   Wikidata; Q54814741
RX   Patent=US5434131;
CC   Group: Patented cell line.
CC   Registration: International Depositary Authority, American Type Culture Collection (ATCC); CRL-10762.
CC   Sequence variation: Gene deletion; UniProtKB; Q2MH30; Dhfr; Zygosity=Heterozygous (from parent cell line).
CC   Sequence variation: Mutation; UniProtKB; Q2MH30; Dhfr; Simple; p.Thr137Arg (c.410G>C); Zygosity=Heterozygous (from parent cell line).
CC   Genetic integration: Method=Transfection; Gene=HGNC; HGNC:2505; CTLA4 (Note=Extracellular domain fused to the hinge, CH2 and CH3 regions of IgC.gamma.1 domain).
CC   Genetic integration: Method=Transfection; Gene=MGI; MGI:94890; Dhfr.
CC   Transformant: ChEBI; CHEBI_23994; Ethyl methanesulfonate (Methylsulfonic acid ethyl ester; MSEE).
CC   Transformant: NCIt; C44386; Gamma radiation.
CC   Derived from site: In situ; Ovary; UBERON=UBERON_0000992.
CC   Cell type: Epithelial cell of ovary; CL=CL_2000064.
OX   NCBI_TaxID=10029; ! Cricetulus griseus (Chinese hamster)
HI   CVCL_1977 ! CHO-DXB11
SX   Female
AG   Adult
CA   Transformed cell line
DT   Created: 04-04-12; Last updated: 19-12-24; Version: 17
//
RX   Patent=US5434131;
RA   Linsley P.S., Ledbetter J.A., Damle N.K., Brady W.;
RT   "Chimeric CTLA4 receptor and methods for its use.";
RL   Patent number US5434131, 18-Jul-1995.
//