ID   Akata 3F2
AC   CVCL_6249
SY   3F2
DR   Wikidata; Q54749085
RX   PubMed=9593003;
RX   PubMed=10022853;
CC   Population: Japanese.
CC   Virology: EBV-negative. Treated with hydroxyurea which completely eliminated EBV episomes.
CC   Sequence variation: Mutation; HGNC; HGNC:11998; TP53; Simple; p.Pro190Leufs*57 (c.569delC); ClinVar=VCV000825904; Zygosity=Unspecified (from parent cell line).
CC   Transformant: NCBI_TaxID; 10376; Epstein-Barr virus (EBV).
CC   Cell type: B-cell; CL=CL_0000236.
DI   NCIt; C27694; EBV-related Burkitt lymphoma
DI   ORDO; Orphanet_543; Burkitt lymphoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_0148 ! Akata
SX   Female
AG   4Y
CA   Cancer cell line
DT   Created: 04-04-12; Last updated: 19-12-24; Version: 18
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RX   PubMed=9593003; DOI=10.1086/515290;
RA   Chodosh J., Holder V.P., Gan Y.-J., Belgaumi A., Sample J.T.,
RA   Sixbey J.W.;
RT   "Eradication of latent Epstein-Barr virus by hydroxyurea alters the
RT   growth-transformed cell phenotype.";
RL   J. Infect. Dis. 177:1194-1201(1998).
//
RX   PubMed=10022853; DOI=10.1128/mcb.19.3.1651; PMCID=PMC83959;
RA   Ruf I.K., Rhyne P.W., Yang H., Borza C.M., Hutt-Fletcher L.M.,
RA   Cleveland J.L., Sample J.T.;
RT   "Epstein-Barr virus regulates c-MYC, apoptosis, and tumorigenicity in
RT   Burkitt lymphoma.";
RL   Mol. Cell. Biol. 19:1651-1660(1999).
//