ID   SK-RC-48
AC   CVCL_6195
SY   SK RC 48; SKRC48
DR   Cosmic; 972919
DR   Wikidata; Q54954595
RX   PubMed=2386958;
RX   PubMed=7915601;
WW   https://www.mskcc.org/research-advantage/support/technology/tangible-material/sk-rc-p-primary-human-renal-cell-carcinoma-rcc-cell-line-collection
CC   From: Memorial Sloan Kettering Cancer Center; New York; USA.
CC   Sequence variation: Mutation; HGNC; 12687; VHL; Simple; p.Leu135Tyrfs*24 (c.404delT); Zygosity=Unspecified (PubMed=7915601).
CC   Miscellaneous: STR profile and age/sex of donor from MSKCC antibody and bioresource core facility.
CC   Derived from site: In situ; Kidney; UBERON=UBERON_0002113.
ST   Source(s): MSKCC
ST   Amelogenin: X
ST   CSF1PO: 12,13
ST   D13S317: 13
ST   D16S539: 11
ST   D18S51: 14
ST   D19S433: 12,16
ST   D21S11: 28,30
ST   D2S1338: 20
ST   D3S1358: 17
ST   D5S818: 12
ST   D7S820: 9,12
ST   D8S1179: 11,13
ST   FGA: 20
ST   TH01: 6,7
ST   TPOX: 8
ST   vWA: 16,18
DI   NCIt; C4033; Clear cell renal cell carcinoma
DI   ORDO; Orphanet_319276; Clear cell renal carcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Male
AG   73Y
CA   Cancer cell line
DT   Created: 04-04-12; Last updated: 29-06-23; Version: 21
//
RX   PubMed=2386958;
RA   Ebert T., Bander N.H., Finstad C.L., Ramsawak R.D., Old L.J.;
RT   "Establishment and characterization of human renal cancer and normal
RT   kidney cell lines.";
RL   Cancer Res. 50:5531-5536(1990).
//
RX   PubMed=7915601; DOI=10.1038/ng0594-85;
RA   Gnarra J.R., Tory K., Weng Y., Schmidt L.S., Wei M.H., Li H., Latif F.,
RA   Liu S., Chen F., Duh F.-M., Lubensky I.A., Duan D.R., Florence C.,
RA   Pozzatti R., Walther M.M., Bander N.H., Grossman H.B., Brauch H.,
RA   Pomer S., Brooks J.D., Isaacs W.B., Lerman M.I., Zbar B.,
RA   Linehan W.M.;
RT   "Mutations of the VHL tumour suppressor gene in renal carcinoma.";
RL   Nat. Genet. 7:85-90(1994).
//